Lysophosphatidic Acid-Mediated Inflammation at the Heart of Heart Failure
Source : https://pubmed.ncbi.nlm.nih.gov/38340272/
Recent findings have shed light on the central role of bioactive lipids, specifically lysophosphatidic acid (LPA) and ceramides, in heart failure pathology. Traditional studies have emphasized factors such as hypoxia-mediated...
This review aimed to bridge the gap between basic research and clinical practice by providing actionable insights and a foundation for the development of targeted therapies that could mitigate the effects of bioactive lipids on heart failure.
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Effect of Unfermented Soy Product Consumption on Blood Lipids in Postmenopausal Women: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Source : https://pubmed.ncbi.nlm.nih.gov/38342411/
The results showed that unfermented soy product consumption significantly reduced TC and TG levels, and increased HDL-C levels in postmenopausal women. The findings of this review contribute to the evidence-base...
Unfermented soy product consumption significantly reduced total cholesterol and triglyceride levels, and increased HDL-C levels in postmenopausal women.
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Identifying High Cholesterol in the Ambulance Setting: a Mixed-Methods Cohort Study to Tackle Health Inequality
Source : https://pubmed.ncbi.nlm.nih.gov/38291949/
Undiagnosed hyperlipidaemia exists in patients using the ambulance service, irrespective of SES. Individual and healthcare system factors prevent engagement in cholesterol lowering behaviours.
Socioeconomic status was not associated with hyperlipidemia or likelihood of seeking further management; rather, it was dictated by competing comorbidities, poor health literacy, and digital divides.
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Cardiometabolic and Renal Phenotypes and Transitions in the United States Population
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615595/
Cardiovascular and renal conditions have both shared and distinct determinants. In this study, we applied unsupervised clustering to multiple rounds of the National Health and Nutrition Examination Survey from 1988...
The cardiometabolic and renal traits of the US population have shifted from phenotypes with high blood pressure and cholesterol toward poor kidney function, hyperglycemia, and severe obesity.
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Ceramides Improve Cardiovascular Risk Prediction Beyond Low-Density Lipoprotein Cholesterol
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10826640/
Low-density lipoprotein cholesterol (LDL-C) is the best documented cardiovascular risk predictor and at the same time serves as a target for lipid-lowering therapy. However, the power of LDL-C to predict...
Ceramides- and phosphatidylcholine-based predictors rather than LDL-C may be used for a more accurate cardiovascular risk prediction in patients at high risk.
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