The Association of Menopause With Cardiometabolic Disease Risk Factors in Low- and Middle-Income Countries: a Systematic Review and Meta-Analyses
This would better inform early monitoring and intervention strategies for reducing CMD risk factor levels in midlife women in these regions. Objective This study aimed to evaluate evidence from the...
Compared with premenopausal women, the postmenopausal stage was associated with metabolic syndrome, high waist-to-hip ratio, hypertension, elevated triglycerides, and elevated plasma glucose.
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Effects of Proprotein Convertase Subtilisin-Kexin Type 9 Inhibitors on Inflammatory and Hemostatic Parameters in Post Myocardial Infarction Patients
Source : https://pubmed.ncbi.nlm.nih.gov/38070635/
Despite progress in treatment, elevated levels of low-density lipoprotein cholesterol (LDL-C) and lipoprotein (a) (Lp(a)), represent a significant part of the residual risk. Both are associated with inflammation and the...
These results show that inflammatory cytokines and fibrinolytic parameters are related to LDL-C and not Lp(a) in patients postmyocardial infarction before and with neither of them following PCSK9 inhibitor treatment.
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Significant Gap Between Guidelines and Practice in the Management of LDL Cholesterol: Insight From the Survey of the Korean Society of Myocardial Infarction
Source : https://pubmed.ncbi.nlm.nih.gov/38147840/
The Guidelines of the 2019 European Society of Cardiology (ESC) and the 5th Society of Lipid and Atherosclerosis (KSoLA) for the Management of Dyslipidemia advocate a more intensive lipid-lowering strategy....
A substantial disparity exists between lipid management guidelines and current clinical practices, highlighting the necessity for clinical research that specifically targets East Asians and Koreans to bridge this gap.
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Glycemic Variability and Time in Range Are Associated With the Risk of Overweight and High LDL-Cholesterol in Children and Youths With Type 1 Diabetes
Source : https://pubmed.ncbi.nlm.nih.gov/38104553/
CGM metrics of glycaemic control and variability were significantly associated with the risk of overweight in females and high LDL-c in both sexes.
Continuous glucose monitoring metrics of glycemic control and variability were significantly associated with the risk of overweight in girls and high LDL-C in both sexes.
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Genetic Insights Into the Association of Statin and Newer Nonstatin Drug Target Genes With Human Longevity: a Mendelian Randomization Analysis
Source : https://lipidworld.biomedcentral.com/articles/10.1186/s12944-023-01983-0
It remains controversial whether the long-term use of statins or newer nonstatin drugs has a positive effect on human longevity. Therefore, this study aimed to investigate the genetic associations between...
Lipid-related gene targets, such as PCSK9, CETP, and APOC3, might potentially regulate human lifespan, thus offering promising prospects for developing newer nonstatin therapies.
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