Clinical characteristics and outcomes in Asian patients with heart failure with mildly reduced ejection fraction
Source : https://journals.lww.com/smj/Abstract/9000/Clinical_characteristics_and_outcomes_in_Asian.99905.aspx
rEF) and preserved ejection fraction (HFpEF). Methods: Patients admitted nationally for HF between 2008 and 2014 were included in the study. They were categorised according to ejection fraction (EF). Patients...
Conclusion: HFmrEF patients account for a significant burden of patients with HF. HFmrEF represents a distinct HF phenotype with high atherosclerotic burden and clinical outcomes saddled in between those of HFrEF and HFpEF. Further therapeutic studies to guide management of this challenging group of patients are warranted.
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Prescribing patterns and factors associated with sodium-glucose cotransporter-2 inhibitor prescribing in patients with diabetes mellitus and atherosclerotic cardiovascular disease - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37311594/
We found that 1 in 5 patients with diabetes and atherosclerotic CVD were prescribed SGLT2 inhibitors in 2019/20, whereas statins were prescribed for 4 of every 5 patients. Although SGLT2...
Interpretation: We found that 1 in 5 patients with diabetes and atherosclerotic CVD were prescribed SGLT2 inhibitors in 2019/20, whereas statins were prescribed for 4 of every 5 patients. Although SGLT2 inhibitor prescribing increased over the study period, disparities in adoption by age, sex, socioeconomic status, comorbidities and physician...
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Noncardiovascular morbidity and mortality across left ventricular ejection fraction catefories following hospitalization for heart failure
Source : https://www.sciencedirect.com/science/article/abs/pii/S1885585723001585?via=ihub
Introducción y objetivos: Los eventos no cardiovasculares son una importante causa de morbimortalidad en pacientes con insuficiencia cardiaca (IC), pe...
Conclusions: Following an admission for HF, LVEF status was directly associated with the risk of noncardiovascular morbidity and mortality. Patients with HFpEF were at higher risk of noncardiovascular death and total noncardiovascular readmissions, especially those with LVEF ≥ 60%.
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Comparison of short and long forms of the Flinders program of chronic disease SELF-management for participants starting SGLT-2 inhibitors for congestive heart failure (SELFMAN-HF): protocol for a prospective, observational study
Source : https://www.frontiersin.org/articles/10.3389/fmed.2023.1059735/full
IntroductionCongestive heart failure (CHF) causes significant morbidity and mortality. It is an epidemic, and costs are escalating. CHF is a chronic disease whose trajectory includes stable phases, periods of decompensation,...
Conclusion: The specific challenges highlighted will be addressed in the creation of hypotheses for future studies. Areas that will be challenging include the CDSM programme for clients from diverse/lower educational and socioeconomic backgrounds where the programme may have variable effectiveness. Delivery to clients placed at the apex of...
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Sex differences in cardiovascular outcomes of SGLT-2 inhibitors in heart failure randomized controlled trials: A systematic review and meta-analysis
Source : https://www.sciencedirect.com/science/article/pii/S2666602223000137?via=ihub
In patients with heart failure (HF), randomized controlled trials (RCTs) of sodium-glucose transporter-2 inhibitors (SGLT-2is) have proven to be effec...
Conclusion: SGLT-2is reduce the risk of primary composite outcomes in patients with HF, regardless of sex; however, the benefits were less pronounced in women. Further research needs to be done to better explain these observed differences in outcomes.
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