Relationship between Canagliflozin, Sodium Glucose Cotransporter 2 Inhibitor, and Hematopoietic Effects in Patients with Diabetes and Mild Heart Failure: Results from the CANDLE trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37070931/
There were few clinical studies on the relationship between sodium glucose cotransporter 2 inhibitors (SGLT2i) and hematopoiesis in patients with diabetes (DM) and heart failure (HF) with consideration of systemic...
Conclusion: cCnagliflozin was associated with an increased hematocrit and hemoglobin in patients with diabetes and HF regardless of their volume status and characteristics.
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Cardio-renal-metabolic syndrome: clinical features and dapagliflozin eligibility in a real-world heart failure cohort - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37095712/
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Conclusions: This study identified high residual risk for all-cause mortality and hospital readmission in real-world HF patients with LVEF < 50% despite GDMT. T2D and CKD aggravated the risk for these endpoints, indicating the intertwinement of HF with CKD and T2D. SGLT2i treatment that clinically benefits these different disease...
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The effect of sodium-glucose cotransporter-2 inhibitors on cardiac structure remodeling and function: A meta-analysis of randomized controlled trials - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37062643/
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Conclusion: Our study showed that SGLT2is, particularly empagliflozin, significantly reverse cardiac remodeling in patients with heart failure. Empagliflozin may be a potentially promising agent to reverse cardiac remodeling in clinical practice.
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Novel Strategies to Improve Prescription of Guideline-Directed Medical Therapy in Heart Failure - Current Treatment Options in Cardiovascular Medicine
Source : https://link.springer.com/article/10.1007/s11936-023-00979-4
Purpose of review To examine the emerging data for novel strategies being studied to improve use and dose titration of guideline-directed medical therapy (GDMT) for patients with heart failure (HF)....
Relevance: A large therapeutic gap between guideline-directed recommendations and real-world practice exists in the contemporary management of patients with HFrEF. Many strategies are being developed in an attempt to close this gap, as outlined in this review.
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Transcatheter Aortic Valve Replacement for Aortic Valve Infective Endocarditis: A Systematic Review and Call for Action - Cardiology and Therapy
Source : https://link.springer.com/article/10.1007/s40119-023-00314-9
We aimed to systematically analyze the literature on the use of transcatheter aortic valve replacement (TAVR) to treat active aortic valve infective endocarditis (AV-IE). Surgery is declined in one-third of...
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