IS BASAL NITRIC OXIDE ACTIVITY OF THE RENAL VASCULATURE ALTERED? ANALYSIS OF A RANDOMIZED CONTROLLED TRIAL COMPARING TWO COMBINATION THERAPIES - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36026660/
1 Department of Nephrology and Hypertension, University Hospital Erlangen, Erlangen, GERMANY. 2 Department of Nephrology and Hypertension, Paracelsus Medical University, Nürnberg, GERMANY. 1 Department of Nephrology and Hypertension, University Hospital...
Conclusions: Basal NO emerged as a determinant of the renal hemodynamic response in the combination therapy of empagliflozin and linagliptin, but not in the combination therapy of insulin and metformin.
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INFLUENCE OF MEAN OFFICE BLOOD PRESSURE(BP) LEVELS ON MORTALITY IN ELDERLY PATIENTS WITH CHRONIC HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF) - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36026726/
In our study, we did not observe differences in mortality between patients with low normal or high SBP, neither on those with high, normal nor low DBP. Although there may...
Conclusions: In our study, we did not observe differences in mortality between patients with low normal or high SBP, neither on those with high, normal nor low DBP. Although there may be a selection bias and this is a retrospective study, more studies are needed to assess the influence of BP control on the evolution of HFpEF in octogenarian...
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Empagliflozin prevents neointima formation by impairing smooth muscle cell proliferation and accelerating endothelial regeneration
Source : https://www.frontiersin.org/articles/10.3389/fcvm.2022.956041/full
BackgroundEmpagliflozin, an inhibitor of the sodium glucose co-transporter 2 (SGLT2) and developed as an anti-diabetic agent exerts additional beneficial effects on heart failure outcomes. However, the effect of empagliflozin on...
Conclusion: Empagliflozin significantly reduces serum-induced proliferation and migration of SMCs in vitro and prevents neointima formation in vivo, while augmenting EC proliferation in vitro and re-endothelialization in vivo after vascular injury. These data document the functional impact of empagliflozin on vascular human SMCs and ECs and...
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Cardiovascular Disease and Health-Related Quality of Life Among Asian American, Native Hawaiian and Pacific Islander Older Adults - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35981219/
Objectives: Assess the relationship between cardiovascular disease (CVD) and health-related quality of life (HRQOL) among Asian American, Native Hawaiian, and Pacific Islander (NH/PI) compared to white older adults. Methods: Data...
Discussion: Asian American and NH/PI older adults with CVD had poorer mental health compared to their white counterparts.
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Thromboinflammation in cardiovascular disease: lessons learned for the management of hypertension, heart failure, and aortic valve stenosis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35979817/
doi: 10.1093/eurheartj/ehac459. Online ahead of print. 1 Department of Cardiology, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germany. 2 Center for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz,...
Conclusion/Relevance: Establishing effective and safe therapies will help to not only improve treatment of hypertension itself, but also to address the adverse outcomes of arterial hypertension such as aortic aneurysm, renal failure, heart failure, and stroke which are the unevitable consequences of this chronic systemic exposure to...
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