Semaglutide in Patients With Obesity-Related Heart Failure and Type 2 Diabetes
Source : https://pubmed.ncbi.nlm.nih.gov/38587233/
Among patients with obesity-related heart failure with preserved ejection fraction and type 2 diabetes, semaglutide led to larger reductions in heart failure-related symptoms and physical limitations and greater weight loss...
Among patients with obesity-related HF with preserved ejection fraction and type 2 diabetes, semaglutide led to larger reductions in HF-related symptoms and physical limitations and greater weight loss than placebo at 1 year.
The models studied performed better than the measurement of N-terminal pro–brain natriuretic peptide level alone.
Left Ventricular Function, Congestion, and Effect of Empagliflozin on Heart Failure Risk After Myocardial Infarction
Source : https://pubmed.ncbi.nlm.nih.gov/38591260/
URL: https://www.clinicaltrials.gov; Unique identifier: NCT03496168.
Empagliflozin reduced the risk for first and total HF hospitalization, irrespective of LVEF or congestion or both.
Low Density Neutrophils and Neutrophil Extracellular Traps (NETs) Are New Inflammatory Players in Heart Failure
Source : https://pubmed.ncbi.nlm.nih.gov/38555028/
HFpEF patients present higher levels of circulating LDNs and NETs related activities, which are the highest in the context of acute HF decompensation.
Patients with HFpEF presented higher levels of circulating low-density neutrophils and neutrophil extracellular trap–related activities.
Sympathetic Neural Control at Rest and During the Cold Pressor Test in Patients With Heart Failure With Preserved Ejection Fraction
Source : https://pubmed.ncbi.nlm.nih.gov/38385250/
Despite augmented resting MSNA burst frequency, burst incidence was not significantly different between groups, and sympathetic baroreflex sensitivity was reduced in patients with HFpEF. Furthermore, patients had preserved sympathetic reactivity...
Despite augmented resting muscle sympathetic nerve activity burst frequency, burst incidence was not significantly different between groups, and sympathetic baroreflex sensitivity was reduced in patients with heart failure with preserved ejection fraction.
Significant associations between the intervention and self-care maintenance, self-care management, self-care confidence, and heart failure knowledge were found.
Fluid and Salt Balance Are Things We Often Overlook: Could Our Understanding of Fluid Dynamics Change How We Tackle Heart Failure?
Source : https://pubmed.ncbi.nlm.nih.gov/38486616/
Fluid and Salt Balance Are Things We Often Overlook: Could Our Understanding of Fluid Dynamics Change How We Tackle Heart failure?
Limiting intake may mitigate the need for such aggressive strategies that could prove detrimental to renal function, systemic blood pressures, and worsen extracardiac symptoms such as cramping or dizziness.
Healthcare Utilization and Left Ventricular Ejection Fraction Distribution in Methamphetamine Use Associated Heart Failure Hospitalizations
Source : https://pubmed.ncbi.nlm.nih.gov/38492945/
While the majority of MU-HF hospitalizations are HFrEF, a sizeable minority have HFpEF. This finding has implications for accurate MU-HF classification, treatment, and prognosis. Patients with MU-HF have low addiction...
Among veterans with methamphetamine use associated heart failure, post–hospital discharge methamphetamine use treatment engagement was low (18% at 30 days postdischarge), with higher follow-up in primary care (76% at 30 days).
Effects of the Valsartan Recall on Heart Failure Patients: a Nationwide Analysis
Source : https://pubmed.ncbi.nlm.nih.gov/38511239/
The valsartan recall did not affect short-term outcomes of heart failure patients. However, the recall potentially disrupted the medication regimens of patients, possibly straining the healthcare system.
The recall potentially disrupted the medication regimens of patients, possibly straining the healthcare system.
High-Sensitivity C-Reactive Protein in Heart Failure With Preserved Ejection Fraction: Findings From TOPCAT
Source : https://pubmed.ncbi.nlm.nih.gov/38307421/
A hsCRP ≥2 mg/L identified HFpEF patients with a high risk of HF events and cardiovascular mortality. Spironolactone did not influence hsCRP levels at 12 months.
A high-sensitivity C-reactive protein level ≥2 mg/L was associated with an increased risk of CV death and HF-related hospital stay.
Greater perceived economic burden was associated with higher risk of 1-year all-cause mortality and worse health status but not with rehospitalization for heart failure.
Red Blood Cell Distribution Width (RDW) Is Associated With Unfavorable Functional Outcome After Transfemoral Transcatheter Aortic Valve Implantation
Source : https://pubmed.ncbi.nlm.nih.gov/38496258/
Elevated preprocedural RDW identifies patients at risk for impaired functional outcome after TAVI and may represent a useful low-cost parameter to guide intensity of outpatient surveillance strategies.
Elevated preprocedural red blood cell distribution width identifies patients at risk for impaired functional outcome after TAVI and may represent a useful low-cost parameter to guide intensity of outpatient surveillance strategies.
Radiomics From Cardiovascular MR Cine Images for Identifying Patients With Hypertrophic Cardiomyopathy at High Risk for Heart Failure
Source : https://pubmed.ncbi.nlm.nih.gov/38385758/
Purpose To develop a model integrating radiomics features from cardiac MR cine images with clinical and standard cardiac MRI predictors to identify patients with hypertrophic cardiomyopathy (HCM) at high risk...
The combined model with radiomics features and clinical and standard cardiac MRI parameters accurately identified patients with hypertrophic cardiomyopathy at high risk for heart failure.
Prehabilitation Using a Cardiac Rehabilitation Program for a Patient With a Total Artificial Heart Prior to Heart Transplantation
This technology aims to address the various subsequent shortfalls of organs. This report reviews the impact of a prehabilitation on a patient with an Aeson TAH (Carmat). Discussion: We assessed...
Similar functional improvements were observed over a short period of 2 weeks compared with a longer protocol for patients with heart transplant.
Prognostic Implication of Heart Failure Stage and Left Ventricular Ejection Fraction for Patients With In-Hospital Cardiac Arrest: a 16-Year Retrospective Cohort Study
Source : https://pubmed.ncbi.nlm.nih.gov/38407585/
HF stage and LVEF could stratify patients with IHCA into different prognoses. Pre-HF and HFpEF were significantly associated with favorable neurological and survival outcomes after IHCA. Further studies are warranted...
Pre-HF and HFpEF were associated with better neurologic and survival outcomes compared with general in-hospital cardiac arrest.
Cost-Effectiveness of a Multidimensional Post-Discharge Disease Management Program for Heart Failure Patients-Economic Evaluation Along a One-Year Observation Period
Source : https://pubmed.ncbi.nlm.nih.gov/38353683
The economic evaluation along the cohort study showed that the HerzMobil Tirol is very cost-effective compared to UC and cost-saving in a sensitivity analysis correcting for "non-HF related costs." These...
A 3-month telemedicine-assisted transitional care service for patients with advanced HF was highly cost effective and improved health outcomes when compared with usual care.
Sex-Related Differences in Patients Presenting With Heart Failure-Related Cardiogenic Shock
Source : https://pubmed.ncbi.nlm.nih.gov/38353681/
In this large HF-CS registry, sex disparities in risk factors and clinical presentation were observed. Despite these differences, the use of treatments was comparable, and both sexes exhibited similarly high...
Women tended to be older but had fewer cardiovascular risk factors and were less likely to present with prevalent HF, a severely depressed LVEF, or with renal dysfunction.
Valve Unit Instead of Intensive or Intermediate Care Unit Admission Following Transcatheter Edge-to-Edge Mitral Valve Repair Is Safe and Reduces Postprocedural Complications
Source : https://link.springer.com/article/10.1007/s00392-024-02384-8
Transcatheter edge-to-edge mitral valve repair (M-TEER) is often performed in general anesthesia, and postprocedural monitoring is usually warranted on an intensive or intermediate care unit (ICU/IMC). We evaluated the implications...
Immediate admission to the valve unit instead of primary ICU/IMC treatment after M-TEER was associated with a significantly shorter hospital stay and a lower incidence of infections and delirium.
Sodium–Glucose Cotransporter-2 Inhibitors in Heart Failure Patients Across the Range of Body Mass Index: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Source : https://link.springer.com/article/10.1007/s11739-024-03532-8
Sodium-glucose cotransporter-2 (SGLT2) inhibitors improve outcomes in patients with heart failure, with or without diabetes. We sought to assess whether there is an interaction of these effects with body mass...
This systematic review and meta-analysis of 14,737 patients with HF and preserved or reduced EF shows that the beneficial effect of empagliflozin and dapagliflozin on CV mortality, all-cause mortality, and HF hospitalization is consistent across the BMI range.
Effect of Carvedilol Versus Placebo on Cardiac Function in Anthracycline-Exposed Survivors of Childhood Cancer (PREVENT-HF): a Randomised, Controlled, Phase 2b Trial
Source : https://pubmed.ncbi.nlm.nih.gov/38215764/
National Cancer Institute, Leukemia & Lymphoma Society, St Baldrick's Foundation, Altschul Foundation, Rally Foundation, American Lebanese Syrian Associated Charities.
Low-dose carvedilol appeared to be safe in long-term childhood cancer survivors at risk for heart failure, but the results did not support use of carvedilol for secondary heart failure prevention in anthracycline-exposed childhood cancer survivors.