PREDICTORS OF CHRONIC HEART FAILURE WITH PRESERVED EJECTION FRACTION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS TREATED WITH EMPAGLIFLOZIN - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36027111/
Currently, it's not well known what factors influenced the incidence of heart failure with preserved ejection (HFpEF) fraction in patients receiving sodium glucose co-transporter 2 inhibitors (SGLT2i). Objective: To evaluate...
Conclusions: Predictors for incidence HFpEF in patients with T2DM were age, diabetes duration, presence of abdominal obesity and galectin-3 levels higher than 10 ng/ml.
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IS BASAL NITRIC OXIDE ACTIVITY OF THE RENAL VASCULATURE ALTERED? ANALYSIS OF A RANDOMIZED CONTROLLED TRIAL COMPARING TWO COMBINATION THERAPIES - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36026660/
1 Department of Nephrology and Hypertension, University Hospital Erlangen, Erlangen, GERMANY. 2 Department of Nephrology and Hypertension, Paracelsus Medical University, Nürnberg, GERMANY. 1 Department of Nephrology and Hypertension, University Hospital...
Conclusions: Basal NO emerged as a determinant of the renal hemodynamic response in the combination therapy of empagliflozin and linagliptin, but not in the combination therapy of insulin and metformin.
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INFLUENCE OF MEAN OFFICE BLOOD PRESSURE(BP) LEVELS ON MORTALITY IN ELDERLY PATIENTS WITH CHRONIC HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF) - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36026726/
In our study, we did not observe differences in mortality between patients with low normal or high SBP, neither on those with high, normal nor low DBP. Although there may...
Conclusions: In our study, we did not observe differences in mortality between patients with low normal or high SBP, neither on those with high, normal nor low DBP. Although there may be a selection bias and this is a retrospective study, more studies are needed to assess the influence of BP control on the evolution of HFpEF in octogenarian...
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Empagliflozin prevents neointima formation by impairing smooth muscle cell proliferation and accelerating endothelial regeneration
Source : https://www.frontiersin.org/articles/10.3389/fcvm.2022.956041/full
BackgroundEmpagliflozin, an inhibitor of the sodium glucose co-transporter 2 (SGLT2) and developed as an anti-diabetic agent exerts additional beneficial effects on heart failure outcomes. However, the effect of empagliflozin on...
Conclusion: Empagliflozin significantly reduces serum-induced proliferation and migration of SMCs in vitro and prevents neointima formation in vivo, while augmenting EC proliferation in vitro and re-endothelialization in vivo after vascular injury. These data document the functional impact of empagliflozin on vascular human SMCs and ECs and...
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Cardiovascular Disease and Health-Related Quality of Life Among Asian American, Native Hawaiian and Pacific Islander Older Adults - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35981219/
Objectives: Assess the relationship between cardiovascular disease (CVD) and health-related quality of life (HRQOL) among Asian American, Native Hawaiian, and Pacific Islander (NH/PI) compared to white older adults. Methods: Data...
Discussion: Asian American and NH/PI older adults with CVD had poorer mental health compared to their white counterparts.
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