Metabolic Dysfunction-Associated Fatty Liver Disease in the Elderly With Diabetic Foot Ulcers: a Longitudinal Cohort Study
Source : https://pubmed.ncbi.nlm.nih.gov/38102851/
This study aimed to explore the association between metabolic-associated fatty liver disease (MAFLD) and ulcer recurrence risk in patients with diabetic foot ulcers (DFUs) through an ambispective longitudinal cohort.
After a median follow-up period of 36 months, patients with metabolic dysfunction-associated fatty livery disease (MAFLD) had a higher ulcer recurrence rate than patients without MAFLD.
A Transcriptome Array-Based Approach to Link SGLT-2 and Intrarenal Complement C5 Synthesis in Diabetic Nephropathy
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10707485/
Diabetic nephropathy is a common microvascular complication of diabetes mellitus. It is characterized by progressive chronic kidney disease (CKD) with decline of kidney function by hyperfiltration. On a mechanistic level,...
SGLT-2 inhibition exerts unequivocal nephroprotective effects by reducing glomerular hyperfiltration and albuminuria, tubular injury, loss of kidney function, and incidence of acute kidney injury.
Effect of Antidiabetic Drugs on Bone Health in Patients With Normal Renal Function and in Chronic Kidney Disease (CKD): Insight Into Clinical Challenges in the Treatment of Type 2 Diabetes
Source : https://www.mdpi.com/2077-0383/12/23/7260
Among the metabolic changes occurring during the course of type 2 diabetes (T2DM) and diabetic kidney disease (DKD), impaired bone health with consequent increased fracture risk is one of the...
Evidence from meta-analyses suggest potential positive effects on fracture risk by metformin and glucagon-like peptide 1 receptor agonists, neutral effects by dipeptidyl peptidase 4 inhibitors, sodium-glucose cotransporter 2 inhibitors, and sulfonylureas, but negative effects by insulin and thiazolidinediones.
Association Between Dietary Insulin Index and Load With Cardiometabolic Risk Factors and Risk of Metabolic Syndrome Among the Patients With Type 2 Diabetes: a Cross-Sectional Study
Source : https://bmcnutr.biomedcentral.com/articles/10.1186/s40795-023-00803-z
This study aims to investigate the association between dietary insulin index (DII) and load (DIL) with cardiometabolic risk factors and the risk of developing metabolic syndrome (MetS) among patients with...
Participants in the highest quartiles of both dietary insulin index and load demonstrated higher odds of metabolic syndrome, hyperglycemia, and increased waist circumference.
Walking Speed and the Risk of Type 2 Diabetes: a Systematic Review and Meta-Analysis
Source : https://bjsm.bmj.com/content/early/2023/11/14/bjsports-2023-107336
We included cohort studies that explored the association between walking speed and the risk of type 2 diabetes in adults.
Dose–response analysis suggested that the risk of type 2 diabetes decreased significantly at a walking speed of 4 km/hour and above.