Type 2 Diabetes Connect
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4yr
Gastrointestinal risk and GLP-1RAs | DMSO

Gastrointestinal risk and GLP-1RAs | DMSO

Source : https://www.dovepress.com/difference-in-gastrointestinal-risk-associated-with-use-of-glp-1-recep-peer-reviewed-fulltext-article-DMSO

Obesity is a global public-health problem. As of 2015, ~2.2 billion are overweight or obese worldwide. Obesity is accompanied by multiple problems, such as reduced exercise capacity, worse quality of...



Conclusion: GLP-1RAs produce a spectrum of distinct classes of GADRs. The individual properties of GADRs between semaglutide and liraglutide might enable incretin-based treatment of obesity to be “tailored” to the needs of each patient.


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4yr

Elevated Circulating Levels of Phenylacetylglutamine in Stroke Patients With T2D Are Linked to Specific Gut Microbiota

Elevated Circulating Levels of Phenylacetylglutamine in Stroke Patients With T2D Are Linked to Specific Gut Microbiota

Source : https://www.researchsquare.com/article/rs-1245321/v1

This preprint is under consideration at Journal of Neuroinflammation. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does...

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    gut microbiota is imbalanced and its metabolite PAGln levels are increased in stroke patients with T2D, and T2D potentially aggravates stroke injury via an inflammatory response, which is associated with Show More
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4yr

The molecular link between oxidative stress, insulin resistance, and type 2 diabetes: A target for new therapies against cardiovascular diseases

Source : https://doi.org/10.1016/j.coph.2021.11.010



Furthermore, some aspects of hypoglycemic therapies and their potential role as antioxidant agents were examined, which might be pivotal in preventing CVD in T2D patients.

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    link between oxidative stress, T2D and CVD may help to further understand the pathological processes beyond this association, to personalize the algorithm of the cure
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4yr
Prevalence and Trends of Type 2 Diabetes Mellitus and Prediabetes among Community-Dwelling Heart Failure Patients in the United States - PubMed

Prevalence and Trends of Type 2 Diabetes Mellitus and Prediabetes among Community-Dwelling Heart Failure Patients in the United States - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35041861/

doi: 10.1016/j.diabres.2022.109191. Online ahead of print. 1 Department of Nutritional Sciences, College of Family and Consumer Sciences, University of Georgia. 305 Sanford Drive, Dawson Hall, Athens, GA 30605, USA. Electronic...

#:~:text=Results: Prevalence rates of diagnosed,44.9%) of HF patients.

Our results suggest that the gut microbiota is imbalanced and its metabolite PAGln levels are increased in stroke patients with T2D, and T2D potentially aggravates stroke injury via an inflammatory response, which is associated with gut microbiota and its metabolite PAGln...

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    Prevention of and targeted intervention for T2DM among at-risk HF patients is needed, particularly among those of Hispanic origin
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    Key Points • Source: Diabetes Research and Clinical Practice • Conclusion/Relevance: “Prevalence rates of T2DM and prediabetes among community-dwelling HF patients in the U.S. remained high between 2005 and 2016. Prevention of and targeted Show More
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4yr
Preoperative plasma aldosterone predicts complete remission of type 2 diabetes after bariatric surgery - PubMed

Preoperative plasma aldosterone predicts complete remission of type 2 diabetes after bariatric surgery - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/35016181/

Introduction: Bariatric surgery (BS) has beneficial effects on body weight and type 2 diabetes. However, 44-52%, 20-40%, and 19-25% of patients with type 2 diabetes who undergo sleeve gastrectomy, sleeve...



Discussion/Conclusion: Preoperative plasma aldosterone levels were related to the CR of type 2 diabetes after BS. Measuring plasma aldosterone levels preoperatively is useful for predicting the CR of type 2 diabetes after BS.