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Low Plasma Adiponectin in Risk of Type 2 Diabetes: Observational Analysis and One- and Two-Sample Mendelian Randomization Analyses in 756,219 Individuals - PubMed

Low Plasma Adiponectin in Risk of Type 2 Diabetes: Observational Analysis and One- and Two-Sample Mendelian Randomization Analyses in 756,219 Individuals - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34426507/

We tested the hypothesis that low plasma adiponectin is observationally and genetic, causally associated with increased risk of type 2 diabetes. Observational analyses are prone to confounding and reverse causation,...

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Effect of Diet Quality and Genetic Predisposition on Hemoglobin A1c and Type 2 Diabetes Risk: Gene-Diet Interaction Analysis of 357,419 Individuals

Effect of Diet Quality and Genetic Predisposition on Hemoglobin A1c and Type 2 Diabetes Risk: Gene-Diet Interaction Analysis of 357,419 Individuals

Source : https://care.diabetesjournals.org/content/early/2021/08/24/dc21-1051

OBJECTIVE To assess the interactions between diet quality and genetic predisposition to incident type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS Between 2006 and 2010, 357,419 participants with genetic and...

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Finerenone benefits patients with diabetes across spectrum of kidney disease

Finerenone benefits patients with diabetes across spectrum of kidney disease

Source : https://www.escardio.org/The-ESC/Press-Office/Press-releases/Finerenone-benefits-patients-with-diabetes-across-spectrum-of-kidney-disease

ESC Press Office Tel: +33 (0) 7 8531 2036Email: [email protected] Follow us on Twitter @ESCardioNews The hashtag for ESC Congress 2021 is #ESCCongress. This press release accompanies both a presentation...

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Non-insulin treatment for A1C reduction in Type 2 diabetes

Current ADA guidelines recommend:




  • A1C goal for nonpregnant adults of <7% (53 mmol/mol) without significant hypoglycemia is appropriate.

  • Achievement of lower A1C levels than 7% may be acceptable, and even beneficial, if achieved safely without significant hypoglycemia or other adverse effects.

  • A1C goals of <8% [64 mmol/mol] or higher may be appropriate for patients with limited life expectancy, or where the risks outweigh the benefits.





Current ADA guidelines recommend that the medication regimen and medication-taking behavior should be reevaluated at regular intervals (every 3–6 months) and adjusted as needed to incorporate specific factors that impact treatment choice.



How long after starting a diabetes medication do you wait to see if the patient needs to switch or escalate to other non-insulin anti-diabetic treatments?



What are the key considerations when deciding to switch or escalate to other non-insulin anti-diabetic treatments?


  • 4yr
    Always encourage pt healthy diet & consult with dietician!
  • 4yr
    Can also consider make adjustments based on their Blood glucose readings !

Show More Comments

  • Saved
Non-insulin treatment for A1C reduction in Type 2 diabetes

Current ADA guidelines recommend:




  • A1C goal for nonpregnant adults of <7% (53 mmol/mol) without significant hypoglycemia is appropriate.

  • Achievement of lower A1C levels than 7% may be acceptable, and even beneficial, if achieved safely without significant hypoglycemia or other adverse effects.

  • A1C goals of <8% [64 mmol/mol] or higher may be appropriate for patients with limited life expectancy, or where the risks outweigh the benefits.





Current ADA guidelines recommend that the medication regimen and medication-taking behavior should be reevaluated at regular intervals (every 3–6 months) and adjusted as needed to incorporate specific factors that impact treatment choice.



How long after starting a diabetes medication do you wait to see if the patient needs to switch or escalate to other non-insulin anti-diabetic treatments?



What are the key considerations when deciding to switch or escalate to other non-insulin anti-diabetic treatments?


  • 4yr
    Always encourage pt healthy diet & consult with dietician!
  • 4yr
    Can also consider make adjustments based on their Blood glucose readings !

Show More Comments