Distinct frontoparietal brain dynamics underlying the co-occurrence of autism and ADHD
Source : https://www.eneuro.org/content/early/2023/06/30/ENEURO.0146-23.2023
Previous diagnostic systems precluded the co-existence of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in one person; but, after many clinical reports, such diagnostic criteria were updated to allow...
Significance statement: Children with autism spectrum disorder (ASD) have cognitive rigidity and tend to persist in specific thoughts, whereas those with ADHD exhibit overly flexible cognition and have trouble with concentration. Despite such contrast, clinically, the two neurodevelopmental disorders are often reported to co-exist in one...
Meaning: This study found no evidence that stimulant treatment, predominantly prescribed in childhood and adolescence, protects against or increases risk of later frequent use of alcohol, cigarettes, marijuana, or other substance use by a mean age of 25 years.
Safety and Tolerability of Serdexmethylphenidate/Dexmethylphenidate Capsules in Children with Attention-Deficit/Hyperactivity Disorder: A 12-Month, Open-Label Safety Study
Source : https://www.liebertpub.com/doi/10.1089/cap.2022.0076
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Conclusions: In this DO, open-label 1-year study, SDX/d-MPH was shown to be safe and well tolerated, with AEs that were comparable with those of other MPH products, with no new or unexpected safety findings. SDX/d-MPH also showed sustained efficacy during the 1-year treatment period.
l-Arginine/nitric oxide pathway and oxidative stress in adults with ADHD: Effects of methylphenidate treatment
Source : https://www.sciencedirect.com/science/article/abs/pii/S1089860323000666?via=ihub
Attention deficit hyperactivity disorder (ADHD) is a mental disorder that was once thought to occur only in children. Meanwhile, it is known that adul...
Conclusion: Adult patients with ADHD, who are not treated with MPH (-MPH), showed varied Arg/NO pathway, but Arg bioavailability seemed to be consistent over the groups. Our findings imply that urinary reabsorption may be increase and/or excretion of nitrite and nitrate may be decreased in ADHD, resulting in an increase in the plasma...
Association between sleep pattern and pharmacological treatment in children with attention deficit disorder with hyperactivity: a systematic review
Source : https://www.scielo.br/j/rpp/a/7VQVW8khwFRmjqgfxcqLCsM/?lang=en
Abstract Objective: The aim of this study was to analyze the effect of the pharmacological...
Conclusions: The drugs used in the treatment of ADHD seem to have negative repercussions on the sleep quality of children, with the drug atomoxetine showing lesser effects on this variable.