Attention-deficit hyperactivity disorder diagnoses and prescriptions in UK primary care, 2000–2018: population-based cohort study
Attention-deficit hyperactivity disorder diagnoses and prescriptions in UK primary care, 2000-2018: population-based cohort study - Volume 9 Issue 4
Meaning: These findings suggest that adolescents’ use of stimulant therapy was not associated with increased risk for illicit stimulant use; however, prescription stimulant misuse was a signal for cocaine or methamphetamine use and warrants monitoring and screening.
Brain tissue iron neurophysiology and its relationship with the cognitive effects of dopaminergic modulation in children with and without ADHD
Source : https://www.sciencedirect.com/science/article/pii/S1878929323000798?via=ihub
Children with attention-deficit/hyperactivity disorder (ADHD) exhibit impairments in response inhibition. These impairments are ameliorated by modulat...
Conclusions/Relevance: Crucially, we observed that higher putamen and caudate tissue iron was associated with greater responsivity to MPH, as measured by improved task performance, in participants with ADHD. These results begin to clarify the role of subcortical brain tissue iron, a measure associated with intrinsic DA availability, in the...
In silico evaluation of the role of lisdexamfetamine on attention-deficit/hyperactivity disorder common psychiatric comorbidities: mechanistic insights on binge eating disorder and depression - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37457000/
Attention-deficit/hyperactivity disorder (ADHD) is a psychiatric condition well recognized in the pediatric population that can persist into adulthood. The vast majority of patients with ADHD present psychiatric comorbidities that have...
Conclusions/Relevance: According to the ANN analysis, proteins targeted by vLDX are predicted to have a high probability of being related to BED and depression. In BED, vLDX was modeled to act upon neurotransmission and neuroplasticity regulators, and, in depression, vLDX regulated the hypothalamic-pituitary-adrenal axis, neuroinflammation,...
Meaning: These findings suggest that adolescents’ use of stimulant therapy was not associated with increased risk for illicit stimulant use; however, prescription stimulant misuse was a signal for cocaine or methamphetamine use and warrants monitoring and screening.
Editorial: Risk and protective factors, family environment and (a)typical neurodevelopmental outcomes
Source : https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1221338/full
only partially predictable and as a whole concerning an open, interacting system that cannot be reduced to simplistic observations of isolated processes concerning the individual child alone (Sander, 2000;Smith &...
Summary: The emerging behavioral epigenetic field provides the neuro-constructivist paradigm with specific biochemical mechanisms that further support the notion by which it is at the interface between genes and environment that developmental trajectories are shaped.