Adherence to Attention Deficit Hyperactivity Disorder (ADHD) medication among the pediatric population is low (≈64%). Nonadherence is related to various factors, including those involving caregivers, the healthcare system, medications, and children themselves. It’s important to address these factors to enhance long-term outcomes.
Experts recommend various interventions to address factors that contribute to nonadherence, including:
- Family education in cases when parents believe that the symptoms are not due to a psychiatric etiology
- Family education when the use of ADHD medication is stigmatized by the family
- Behavior strategies (eg, Cognitive-Behavioral Therapy) when there is conflict between the caregiver and child regarding treatment or when the child refuses to take the ADHD medication
- Behavior strategies (eg, behavioral parent training, multisystemic therapy for conduct disorder) when comorbidities (eg, oppositional defiant disorder, conduct disorder) interfere with the child’s ability to take ADHD medication
- Clinician intervention in cases of medication ineffectiveness, adverse events, multiple daily doses/onerous medication regimen, and a paucity of medication titration
When ADHD drugs are more effective, medication adherence improves. Dosing factors and medication titration are also associated with improved adherence. Using a streamlined dose regimen can increase adherence, with patients prescribed long-acting formulations having higher rates of adherence than those prescribed short-acting formulations.
Long-acting stimulants may yield more balanced and sustained effects on ADHD symptoms throughout the day. The burden of taking multiple daily doses and the stigma of mid–school-day dosing could also attenuate adherence in children taking short-acting formulations.
What is your clinical experience with long-acting stimulants for ADHD? What factors could boost adherence in your patients?
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Darin Skaudis, Physician1yrShort or frequent dosed medications worsen compliance compared to extended release options. -
Paul Vollmar, Community hospital2yrI’m always surprised by the number of my patients that don’t fill their scripts.


