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2yr
ADHD in Narcolepsy: a Closer Look at Prevalence and Ties

ADHD in Narcolepsy: a Closer Look at Prevalence and Ties

Source : https://www.sciencedirect.com/science/article/abs/pii/S0149763423004402?via=ihub

The reported prevalence of attention deficit hyperactivity disorder (ADHD) in narcolepsy varies considerably, while the associated factors remain....

This meta-analysis of 4 studies with healthy control groups showed that the OR for ADHD in patients with narcolepsy was approximately 10 times higher compared with healthy controls.

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2yr
Receiver Operating Characteristic Curve Analysis of the Weiss Functional Impairment Rating Scale-Parent Report for Screening Children With ADHD: Looking Beyond Symptoms in ADHD Diagnosis

Receiver Operating Characteristic Curve Analysis of the Weiss Functional Impairment Rating Scale-Parent Report for Screening Children With ADHD: Looking Beyond Symptoms in ADHD Diagnosis

Source : https://pubmed.ncbi.nlm.nih.gov/38030566/

The WFIRS-P is a sensitive and specific measure of the functional impairment associated with ADHD in Iranian children. Our sample was predominantly male, limiting the generalizability of results to females.

The self-concept and life skills subscales had low sensitivity, suggesting some mothers do not identify problems with self-concept or difficulty with life skills as particularly problematic in ADHD.

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2yr
Guanfacine and Methylphenidate Improved Chronic Lower Back Pain in Autosomal Dominant Polycystic Kidney Disease With Comorbid Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder

Guanfacine and Methylphenidate Improved Chronic Lower Back Pain in Autosomal Dominant Polycystic Kidney Disease With Comorbid Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder

Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646415/

Autosomal dominant polycystic kidney disease (ADPKD) is an inherited renal disease characterized by the bilateral development of multiple cysts in the kidneys.

This case demonstrated that ADPKD can coexist with ADHD and autism spectrum disorder; guanfacine and methylphenidate can improve chronic pain in ADPKD; and cerebral blood flow can improve during the treatment course.

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2yr
Word-Finding Difficulties as a Prominent Early Finding in a Later Diagnosis of Attention Deficit Hyperactivity Disorder

Word-Finding Difficulties as a Prominent Early Finding in a Later Diagnosis of Attention Deficit Hyperactivity Disorder

Source : https://pubmed.ncbi.nlm.nih.gov/38029778/

Preliminary evidence supports a predictive link between preschool WFDs and later ADHD diagnosis, highlighting the importance of early WFDs clinical attention.

Among children with a history of word-finding difficulty, 93% were later diagnosed with ADHD compared with 42% in children without such history, and this relationship was significant.

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2yr
The supply crisis involving ADHD medications

Many parents are frustrated with the current reality that the regular stimulant medication for their child with Attention Deficit Hyperactivity Disorder (ADHD) is out of stock at local pharmacies. The reasons underlying this shortage are complex and multifactorial.

The COVID-19 pandemic altered the supply chain for ADHD medications and resulted in shortages in a market that was already tightly restricted. Because of the suspension in January 2020 of the Ryan Haight Online Pharmacy Consumer Protection Act of 2008, the total number of psychostimulant prescriptions rose by 10% among American adolescents and adults. Of note, the Ryan Haight Act tightly regulated the ability of telepsychiatry providers to prescribe controlled substances. In addition, certain companies are taking aim at individuals for whom ADHD medications are not indicated. Former U.S. government lawyers/employees have denounced some start-ups for prioritizing profit over patient well-being.

Despite awareness of a shortfall in psychostimulant supplies since 2021, U.S. regulators have been slow to react. Although the FDA has announced plans to update boxed warnings to mitigate misuse by patients and prescribers, this step will not alleviate the supply issues.

What steps can be taken to mitigate the short supply and provide increased access to psychostimulants to children with ADHD?

  • 2yr
    The supply problem is not limited to ADHD medications. I do not know all of the factors behind this, but I think there needs to be more domestic production Show More
  • 2yr
    Firstly, we have to make sure that we are screening and diagnosing patients appropriately for ADHD. Lots of medical conditions can mask or occur concurrently with ADHD. Sadly, lots of Show More

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