Perceived Expressed Emotion and Irritability in Adolescents With Attention-Deficit/Hyperactivity Disorder Inattentive Type: The Moderating Effect of Subtype | Journal of Psychosocial Nursing and Mental Health Services
Source : https://journals.healio.com/doi/10.3928/02793695-20220429-01
The current study aimed to investigate perceived expressed emotion (EE) and irritability among adolescents with inattentive and combined type attention-deficit/hyperactivity disorder (ADHD-I and ADHD-C, respectively), and to assess whether the...
Conclusion: Results of moderation analysis showed ADHD subtype to be a moderating factor in the relationship between perceived EE and irritability.
Acute Hyperkinetic Movement Disorders as a Multifactorial Pharmacodynamic Drug Interaction Between Methylphenidate and Risperidone in Children and Adolescents - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35489029/
As outlined in changes to the US prescribing information for all methylphenidate and risperidone products, health care professionals should be aware that changes to this combination may be associated with...
Implications/conclusions: As outlined in changes to the US prescribing information for all methylphenidate and risperidone products, health care professionals should be aware that changes to this combination may be associated with a pharmacodynamic drug-drug interaction resulting in acute hyperkinetic movement disorder.
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ADHD Connect3yrKey Points • Source: Journal of Clinical Psychopharmacology • Implications/Conclusions: “As outlined in changes to the US prescribing information for all methylphenidate and risperidone products, health care professionals should be aware that changes to Show More
A view of response and resistance to atomoxetine treatment in children with ADHD: effects of CYP2C19 polymorphisms and BDNF levels - European Journal of Clinical Pharmacology
Source : https://link.springer.com/article/10.1007/s00228-022-03321-2
Objective Although several genes have previously been studied about the treatment of Attention Deficit Hyperactivity Disorder (ADHD), the number of studies investigating the effects of genes on atomoxetine (ATX) treatment...
Conclusions:To our knowledge, this is the first study to assess the effects of CYP2C19 polymorphisms and BDNF levels together on ATX treatment in children. Further studies with an extensive population are needed to better understand the effects of CYP2C19 polymorphisms on treatment and side effects, as well as the effects of BDNF levels.
Influence of Maternal Diabetes on the Risk of Neurodevelopmental Disorders in Offspring in the Prenatal and Postnatal Periods - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35488357/
doi: 10.4093/dmj.2021.0340. Online ahead of print. 1 Endocrinology and Nutrition Department, University Hospital Mutua de Terrassa, Terrassa, Spain. 2 Obstetrics and Gynecology Department, University Hospital Mutua de Terrassa, Terrassa, Spain....
Conclusion: Prenatal exposure to GDM increases the risk of ADHD in offspring, regardless of GDM treatment complexity. However, postnatal exposure to maternal T2DM was not related to the development of ADHD.
Virtual Ontogeny of Cortical Growth Preceding Mental Illness
Source : https://www.biologicalpsychiatryjournal.com/article/S0006-3223(22)01067-8/fulltext
Morphology of the human cerebral cortex differs across psychiatric disorders, with neurobiology and developmental origins mostly undetermined. Deviations in the tangential growth of the cerebral cortex during pre/perinatal periods may...
Conclusions: Our findings support a neurodevelopmental model of vulnerability to mental illness whereby prenatal risk factors acting through cell-specific processes lead to deviations from typical brain development during pregnancy.