Hepatitis Delta in HIV/Hepatitis B Coinfection: a Call for Action
Source : https://pubmed.ncbi.nlm.nih.gov/37968830/
Hepatitis delta in HIV/hepatitis B coinfection: a call for action
In people living with HIV infection who are at a particularly high risk of liver disease-related complications, in the presence of underlying hepatitis B/D virus coinfection, hepatitis D virus represents a frequently underdiagnosed critical health issue that needs more attention and research.
Pilot Randomized Controlled Trial of Game Plan for PrEP: a Brief, Web and Text Message Intervention to Help Sexual Minority Men Adhere to PrEP and Reduce Their Alcohol Use
Source : https://link.springer.com/article/10.1007/s10461-023-04223-9
Suboptimal adherence to oral PrEP medications, particularly among younger sexual minority men (SMM), continues to be a key barrier to achieving more substantial declines in new HIV infections. Although variety...
This pilot study explored whether the Game Plan for PrEP, a brief, web-based and text messaging intervention, helped promote PrEP persistence and adherence and reduced condomless sex and alcohol use.
Ex Vivo Rectal Tissue Infection With HIV-1 to Assess Time to Protection Following Oral PrEP With TDF/FTC (a Sub-Study of the ANRS PREVENIR Study)
Participants from the ANRS PREVENIR study (NCT03113123) were offered this sub-study after a 14-day wash-out. We used an ex vivo model to evaluate rectal tissue HIV-1 susceptibility before and after...
Oral tenofovir disoproxil and emtricitabine provided similar protection against HIV-1 infection of rectal tissue 2 hours after a double dose or 7 days of a daily dose.
Global, Regional, and Country-Level Coverage of Testing And Treatment for HIV and Hepatitis C Infection Among People Who Inject Drugs: a Systematic Review
Source : https://pubmed.ncbi.nlm.nih.gov/37973339/
Australian National Health and Medical Research Council and UK National Institute for Health and Care Research Health Protection Research Unit in Behavioural Science and Evaluation.
The findings of this study show the crucial need for producing quality data on HIV and HCV care coverage among people who inject drugs at a country level.
Current ART, Determinants for Virologic Failure and Implications for HIV Drug Resistance: an Umbrella Review
Source : https://aidsrestherapy.biomedcentral.com/articles/10.1186/s12981-023-00572-6
The purpose of this study is to investigate the incidence of determinants for virologic failure and to identify predisposing factors to enhance treatment efficacy. Tackling this global public health issue...
This article highlights several primary causes of treatment failure, including poor adherence to medication, low CD4 T-cell counts, high viral levels, and specific types of regimens used.