Comparison of Metabolic Effects of Three Different Treatment Combinations With Retrospective Real-life Data in People Living With HIV
Source : https://www.eurekaselect.com/article/136163
Comorbidities are increasing in people living with HIV (PLHIV), and different treatment options have advantages and disadvantages. It is important to compare information from real-life treated cases. The aim of...
Although CD4 elevation is lower in EFV recipients than in INSTI recipients, weight gain is higher in INSTI recipients.
Incarceration History Is Associated With HIV Infection Among Community-Recruited People Who Inject Drugs in Europe: a Propensity-Score Matched Analysis of Cross-Sectional Studies
Source : https://pubmed.ncbi.nlm.nih.gov/37991429/
A history of incarceration appears to be independently associated with HIV infection among people who inject drugs (PWID) in Europe, with a stronger effect among PWID with lower probability of...
Incarceration was associated with 30% higher odds of HIV infection. The association between a history of incarceration and HIV infection was strongest among people who inject drugs.
Clinical Significance and Management of Low-Level HIV Viremia in the Era of Integrase Strand Transfer Inhibitors
Source : https://pubmed.ncbi.nlm.nih.gov/37990782/
This review aims to assess recent findings to provide a view of the clinical significance and management of low-level HIV viremia in the era of INSTIs.
Integrase strand transfer inhibitor-based therapies could lead to lower low-level viremia over time, thereby leading to more effective virologic control.
Fetal Growth Assessed Via Ultrasound in Relation to Maternal HIV Infection Status and Antiretroviral Regimens
We evaluated fetal growth via repeated ultrasounds and calculated Z-scores for fetal growth measures using Intergrowth-21st standards among women with singleton pregnancies. Adjusted linear mixed models were fit for each...
Fetal growth was lower in women living with HIV (WLHIV) than those not living with HIV early in gestation but similar by the end of gestation. Among WLHIV, fetal growth measures were generally similar across antiretroviral regimens evaluated.
HIV-2 Inhibits HIV-1 Gene Expression Via Two Independent Mechanisms During Cellular Co-Infection
Source : https://pubmed.ncbi.nlm.nih.gov/37991365/
Twenty-five years after the first report that HIV-2 infection can reduce HIV-1-associated pathogenesis in dual-infected patients, the mechanisms are still not well understood. We explored these mechanisms in cell culture...
Under specific conditions, HIV-2 inhibits HIV-1 through 2 distinct mechanisms, a broad-spectrum interferon response and an HIV-1-specific inhibition conferred by the HIV-2 TAR.