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EP089/#784 Low use of hormone therapy in women with early menopause arising from treatment for cervical cancer

EP089/#784 Low use of hormone therapy in women with early menopause arising from treatment for cervical cancer

Source : https://ijgc.bmj.com/content/32/Suppl_3/A84.2

Objectives Many cervical cancer patients are premenopausal at diagnosis, and the treatment induces early menopause. The aim of this study was to evaluate the frequency of hormone replacement therapy (HRT)...



Conclusion: A small percentage of cervical cancer survivors have adequate information about menopause and HRT, and a smaller proportion receive hormone replacement therapy. These data show the need for attention to these young women who have menopause arising from treatment, and reinforce the importance for survivorship guidelines for cervical...

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Association of ß-glucuronidase activity with menopausal status, ethnicity, adiposity, and inflammation in women

Association of ß-glucuronidase activity with menopausal status, ethnicity, adiposity, and inflammation in women

Source : https://journals.lww.com/menopausejournal/Abstract/9900/Association_of___glucuronidase_activity_with.111.aspx

le is known about ß-glucuronidase regulation across women's reproductive lifespan. Correlates of serum ß-glucuronidase activity in healthy premenopausal versus postmenopausal women were therefore examined. Methods ß-Glucuronidase activity and C-reactive protein...



Conclusion: ß-Glucuronidase enzyme activity, upon which polyphenol health-related benefits may depend, is not associated with menopausal status. Future studies are required to determine clinical significance and mechanisms driving ß-glucuronidase associations with ethnicity, inflammation, and adiposity in women.

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Heart Failure in Menopause: Treatment and New Approaches

Heart Failure in Menopause: Treatment and New Approaches

Source : https://www.mdpi.com/1422-0067/23/23/15140/htm

Aging is an important risk factor for the development of heart failure (HF) and half of patients with HF have preserved ejection fraction (HFpEF) which is more common in elderly...



Conclusion: Despite all the advances in considering the best options to treat menopause-induced HFpEF, which involves the reduction of cardioprotection due to estrogen depletion, the focus should be the modulation of the RAS and sympathetic system. The combination of the alternatives described and lifestyle changes including physical activity...

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Vitamin D supplements and prevalent overactive bladder in women from midlife through older ages

Vitamin D supplements and prevalent overactive bladder in women from midlife through older ages

Source : https://journals.lww.com/menopausejournal/Abstract/2022/12000/Vitamin_D_supplements_and_prevalent_overactive.9.aspx

ate the association of vitamin D supplements with prevalent OAB, all of which were reported by participants in 2019 in both NHS cohorts. OAB was defined as the self-reported need...



Conclusion: OAB symptoms are highly prevalent across adult women, including the oldest old, who are often excluded from treatment trials. Despite interest in vitamin D supplementation as a low-cost strategy to address OAB, our findings indicate oral vitamin D is not associated with prevalent OAB in middle-aged and older women.

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The correlation of the fecal microbiome with the biochemical profile during menopause: a Brazilian cohort study - BMC Women's Health

The correlation of the fecal microbiome with the biochemical profile during menopause: a Brazilian cohort study - BMC Women's Health

Source : https://bmcwomenshealth.biomedcentral.com/articles/10.1186/s12905-022-02063-8

Background Hormonal, biochemical, and metabolic changes after menopause may alter the quality of life of women, leading to vasomotor, psychological, and genitourinary symptoms, and changes in their gut microbiota, which...



Conclusion: The hormonal and metabolic changes during menopause in the population studied were accompanied by a significant change in the fecal microbiota, especially of the genus Clostridium.

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