Menopause hormone therapy and complementary alternative medicine, quality of life, and racial/ethnic differences: the Study of Women's Health Across the Nation (SWAN)
Source : https://doi.org/10.1097/GME.0000000000002087
of HT and CAM with QoL. Methods Cross-sectional and longitudinal analyses of QoL in the Study of Women's Health Across the Nation participants using HT, CAM, or both. Women (n...
Conclusion: Comparisons between treatment type within each racial/ethnic group yielded significant differences in self-reported QoL. Clinicians should be aware of racial/ethnic differences in treatment preferences when counseling patients on treatment options for menopausal symptoms to provide optimal care.
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The Relationship Between Menopause and Dysphagia: A Scoping Review
Source : https://www.liebertpub.com/doi/10.1089/whr.2022.0078
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Conclusion: Although menopause is known to adversely affect structures and functions related to swallowing such as bone, muscle, and mucosa of the upper aerodigestive tract, saliva, and taste, the relationship between menopause and swallowing functions remains poorly understood. By identifying the major gaps in the literature, these results...
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Effects of resistance training on C-reactive protein in menopausal and postmenopausal women: a systematic review and meta-analysis of randomized controlled trials
We searched PubMed, Embase, CENTRAL, Scopus, and Web of Science from inception to 2021, and clinical trial registries. Randomized controlled trials (RCT) in menopausal and postmenopausal women that compared women...
Discussion: There was very low-quality evidence supporting the benefits of RT compared with control for C-reactive protein levels and lipid profile. No benefits were found for the outcome of waist circumference in postmenopausal women with different comorbidities or risk factors.
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Bring the life stages into the domain of basic and clinical pharmacology
Source : https://www.frontiersin.org/articles/10.3389/fphar.2022.923016/full
Completely distinct physiological conditions and immune responses exist among different human life stages. Age is not always consistent with the life stage. We proposed to incorporate the concept of the...
Conclusion: No matter influenced by which factors, life stages such as puberty and menopause are the indication of significant changes in human development. Because the ages of puberty among individuals or ethnic groups are different, instruction of doses is better based on puberty rather than ages.
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Novel insights into reproductive ageing and menopause from genomics - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36478237/
The post-reproductive phase or menopause in females is triggered by a physiological timer that depends on a threshold of follicle number in the ovary. Curiously, reproductive senescence appears to be...
Conclusion: Recent large scale genomic studies have started to elucidate how genetic variation affects variation in the ANM and importantly has informed functional experiments targeting specific molecular players for pharmacological or life-style treatments. Following the example of other complex traits, larger cohorts are anticipated to expand...
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