Possible Association of Hysterectomy Accompanied with Opportunistic Salpingectomy with Early Menopause: A Retrospective Cohort Study
Source : https://www.mdpi.com/1660-4601/19/19/11871
Opportunistic salpingectomies (OSs) are concurrently performed with hysterectomies to prevent epithelial ovarian cancer. This study aimed to investigate the correlation between OS and early menopause in females who have undergone...
Conclusion: These results showed that a hysterectomy plus an OS might cause earlier menopause than a hysterectomy only. An OS should be preoperatively discussed with patients regarding the possibility of early menopause. The findings of this study require further large-scale investigations to reinforce the results.
Low Handgrip Strength, Obesity Associated With Increased Risk of CKD in Women
A study published in The Journal of The North American Menopause Society found that postmenopausal women who had low handgrip strength and a high waist circumference, defined here as dynapenic-abdominal...
Conclusion: The researchers concluded that there was an association of dynapenic-abdominal obesity, determined by hand grip strength and abdominal obesity, with CKD in women post-menopause.
Global hotspots and prospects of perimenopausal depression: A bibliometric analysis via CiteSpace
Source : https://www.frontiersin.org/articles/10.3389/fpsyt.2022.968629/full
BackgroundPerimenopausal depression (PMD) is characterized by affective symptoms as well as menopause-specific somatic complaints and has attracted increasing attention over the past few decades. Using a bibliometric tool, this study...
Discussion: These findings provide us with the core countries, institutions, and authors in PMD research and point out the direction of attention in this field. The current research focuses on depression, postmenopausal women, hot flashes, and other symptoms, as well as the prevalence and risk factors.
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Menopause Connect4yrKey Points • Source: Frontiers in Psychiatry • Conclusion: “This is the first study to use CiteSpace to perform bibliometric analysis and provide a visual display of publications on PMD from the cooperation among Show More
Conclusion: This large, population-based cohort study found that sex-specific risk factors were associated with the risk of new-onset AF among women. The AF risk was elevated among women with early or delayed menopause. In addition, women with irregular menstrual cycles had a greater risk for AF onset. Both nulliparity and multiparity were...
Statins provide protective immune benefits for females
Source : https://www.eurekalert.org/news-releases/962681
When we have too much cholesterol, it can build up in the walls of our arteries and cause cardiovascular disease. But cholesterol molecules play a critical role in our cells'...
Conclusion: Andersen found that statins, commonly prescribed lipid-lowering drugs, provide a protective immune function in females.
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Dr Hamid4yrThis study and it’s findings is especially significant because historically, drug trials have used predominantly male participants
Relation Between Sex, Menopause, and White Matter Hyperintensities
Source : https://n.neurology.org/content/99/9/e935.abstract
Background and Objectives Mounting evidence implies that there are sex differences in white matter hyperintensity (WMH) burden in older people. Questions remain regarding possible differences in WMH burden between men...
Discussion: After menopause, women displayed a higher burden of WMH than contemporary premenopausal women and men and an accelerated increase in WMH. Sex-specific effects of uncontrolled hypertension on WMH were not related to menopause.
Immunization for midlife women - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35998660/
Objective: Menopause occurs at a critical juncture in life when preventative health care can have a major impact. However, recommendations for immunizations are often neglected, leading to unnecessary morbidity and...
Conclusion: As women often seek medical attention at menopause because of changes in their physiology that require attention, it is the ideal time to discuss the importance of immunization.
Differing effects of oral conjugated equine estrogen and transdermal estradiol on vitamin D metabolism in postmenopausal women: a 4-year longitudinal study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35969885/
Directly measured free 25-hydroxyvitamin D levels, but not serum total 25-hydroxyvitamin D levels, are different within the first 12 months of estrogen replacement depending on the preparation. However, this difference...
Conclusion: Directly measured free 25-hydroxyvitamin D levels, but not serum total 25-hydroxyvitamin D levels, are different within the first 12 months of estrogen replacement depending on the preparation. However, this difference is transient, in that there were no differences at 36 or 48 months.
Conclusion: This cohort study found a risk for ENM in women with laparoscopically confirmed endometriosis. These women compared with those without endometriosis may be at a higher risk for shortened reproductive duration, particularly those who were nulliparous or never used oral contraceptives
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Dr Hamid4yrstudy suggest that women with endometriosis may be at a higher risk for a shortened reproductive duration
Updated Perspectives on the Role of Estrogens in Skin Aging | CCID
Source : https://doi.org/10.2147/CCID.S333663
For many years, it has been recognized that estrogens are important in the maintenance of human skin. Women seek cosmetic and medical treatments to improve dermal health and physical characteristics...
Conclusion: Especially where skin collagen and elastin profiles are known to follow 17β-estradiol levels during aging and at/after menopause. Finally, the classification of isoflavonoid compounds as endocrine disruptors is unwarranted. In fact, isoflavonoids act as SERMs that bind to ER in the skin to enhance dermal health. Whereas the topical...
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Menopause Connect4yrKey Points • Source: Clinical, Cosmetic and Investigational Dermatology • Relevance: “The narrative for this overview focuses on updating the factors that influence skin aging and the important role estrogens and selective estrogen receptor Show More
Genitourinary Syndrome of Menopause
Source : https://effectivehealthcare.ahrq.gov/products/genitourinary-syndrome/key-questions
Introduction The Patient-Centered Outcomes Research Institute (PCORI) is partnering with the Agency for Healthcare Research and Quality (AHRQ) to develop a systematic evidence review on Genitourinary Syndrome of Menopause. The...
Discussion: The negative effect of GSM on quality of life is substantial; as many as 85% of patients over 40 years of age report vaginal dryness, 29-59% report dyspareunia, 26-77% report vaginal itching and irritation and 40-68% report negative consequences on their sex life, including decreased sexual satisfaction and frequency.
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Regina George4yrI use estradiol vaginal cream on any female post menopausal who c/o dryness and dyspareunia. Per ACOG even breast cancer survivors can use it.
Menopausal Symptoms and Sleep Quality in Women Aged 40-65 Years
Source : https://www.hindawi.com/journals/bmri/2022/2560053/
The study examined the relationship between menopausal symptoms and sleep disturbances and the related influencing factors. Methods . We recruited women aged 40-65 years who attended the menopause clinic at...
Conclusion: Menopausal symptoms are strongly correlated with the degree of sleep disorders. Menopausal syndrome palliation may alleviate the severity of sleep disorders in women.
Menopause and oral health - British Dental Journal
Source : https://www.nature.com/articles/s41415-022-4568-0
Sir, the oral health effects of changes in certain hormone levels during pregnancy, namely in the form of pregnancy gingivitis, are well recognised with a large body of research and...
Discussion: We ask dental professionals to be conscious of the menopause when managing this cohort of patients, whose oral health may be at risk akin to women in pregnancy. We hope with a larger research base and guidance, we can inform, advise and treat this large cohort of patients more appropriately in years to come.
Gut microbiome in menopause | IJWH
At current life expectancy, women on average spend approximately three decades of life post-menopause. This significant life chapter is met with elevated risk of age-related chronic diseases, such as diabetes...
Conclusion: the research to date on menopause, female sex hormones, and the gut microbiome suggests that menopause and/or low estrogens are associated with reduced gut microbiome diversity and estrobolome potential, and greater similarity to men in microbiome composition. Additionally, declines in estradiol and progesterone may lead to...
Survey: Middle-Aged Women Frequently Report Cannabis Use to Mitigate Menopause Symptoms - NORML
Belmont, MA: Many middle-aged women acknowledge consuming cannabis products to alleviate menopause-related symptoms, according to survey data published in the journal Menopause. A team of researchers affiliated with McLean Hospital...
Discussion: The current study indicates that many individuals are currently using commercially available MC [medical cannabis] products as an adjunct treatment for menopause-related symptoms.
Investigating trends in those who experience menstrual bleeding changes after SARS-CoV-2 vaccination - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35857495/
Early in 2021, many people began sharing that they experienced unexpected menstrual bleeding after SARS-CoV-2 inoculation. We investigated this emerging phenomenon of changed menstrual bleeding patterns among a convenience sample...
Conclusion: We found that increased/breakthrough bleeding was significantly associated with age, systemic vaccine side effects (fever and/or fatigue), history of pregnancy or birth, and ethnicity.
Discussion: These results are consistent with the findings of prior studies and emphasize that factors other than use of hormone therapy, such as higher importance of sex, positive attitudes toward sex, satisfaction with one’s partner, and fewer genitourinary symptoms associated with menopause appear to be protective and are linked to...
Premature menopause is associated with increased risk of heart problems
Sophia Antipolis, 4 August 2022 : Menopause before 40 years of age is associated with elevated risks of heart failure and atrial fibrillation, according to a study published today in...
Conclusion: Our study indicates that reproductive history should be routinely considered in addition to traditional risk factors such as smoking when evaluating the future likelihood of heart failure and atrial fibrillation.
Conclusion: Our findings suggest that postmenopausal women with a history of premature menopause or early menopausal age may have an increased risk of HF and AF. These reproductive factors need to be considered for preventing the future risk of HF and AF.
Patterns of Sexual Activity and the Development of Sexual Pain Across the Menopausal Transition - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35675610/
Long-term and short-term declines in sexual intercourse frequency across the menopausal transition were not associated with increased hazard of developing pain with intercourse. This empirical evidence does not support the...
Conclusion: Long-term and short-term declines in sexual intercourse frequency across the menopausal transition were not associated with increased hazard of developing pain with intercourse. This empirical evidence does not support the common belief that a reduction in women's sexual frequency is responsible for their symptoms of sexual pain.