Virgin Coconut Oil in Paste Form as Treatment for Dyspareunia and Vaginal Dryness in Patients With and Without Rheumatic Autoimmune Diseases: An Efficacy and Safety Assessment Pilot Study
Introduction The use of virgin coconut oil (VCO) as an over-the-counter (OTC) treatment for vaginal dryness and dyspareunia (VDD) in the general population has increased worldwide despite the absence of...
Conclusion: A high percentage of women with VDD, with and without RAD, needlessly continue to experience quality-of-life-altering physical and psychosocial morbidity due to the underutilization and lack of awareness of VCO-containing therapy. The small sample size, non-blinded, non-randomized, pilot platform, and the use of a non-validated...
Skin cancer risk of menopausal hormone therapy in a Korean cohort - Scientific Reports
Source : https://www.nature.com/articles/s41598-023-37687-9
Conflicting studies exist on the association between menopausal hormone therapy (MHT) and skin cancers, such as melanoma and non-melanoma skin cancer (NMSC). This retrospective cohort study aimed to evaluate the...
Discussion: Overall, MHT was not associated with melanoma incidence in menopausal Korean women. Instead, tibolone and COPM were associated with a decrease in NMSC occurrence.
Menopausal hormone therapy and dementia: nationwide, nested case-control study
Source : https://www.bmj.com/content/381/bmj-2022-072770
Objectives To assess the association between use of menopausal hormone therapy and development of dementia according to type of hormone treatment, duration of use, and age at usage. Design Nationwide,...
Conclusion: Menopausal hormone therapy was positively associated with development of all cause dementia and Alzheimer’s disease, even in women who received treatment at the age of 55 years or younger. The increased rate of dementia was similar between continuous and cyclic treatment. Further studies are warranted to determine whether these...
Frequency of Thyroid Disorder in Pre- and Postmenopausal Women and Its Association With Menopausal Symptoms
Background Thyroid hormone has a significant effect on women's life. Its dysfunction is widespread, particularly among women over 50. Understanding how thyroid disease's clinical symptoms change with aging is crucial...
Conclusion: The present study concludes that thyroid disorder is common among pre- and postmenopausal age group women. Therefore, timely detection and intervention should be taken into consideration, and even if the thyroid level is found to be normal still lifestyle modification and counselling can help in improving the quality of life.
Vasomotor and other menopause symptoms and the prevalence of ideal cardiovascular health metrics among premenopausal stage women
g health screening examinations. Menopause symptoms were measured using the Korean version of the Menopause-Specific Quality of Life questionnaire. For vasomotor, psychosocial, physical, and sexual symptoms, participants were divided into...
Conclusion: Premenopausal stage women with either vasomotor or nonvasomotor menopausal symptoms have significantly higher prevalence of poor CVH metrics, compared with those without any menopausal symptoms.
Age But not Menopausal Status is Linked to Lower Resting Energy Expenditure
Source : https://academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgad321/7188953
AbstractContext. It remains uncertain whether aging before late adulthood and menopause are associated with fat-free mass and fat mass-adjusted resting energy e
Conclusion: We demonstrated that REEadj declines with age in women before late adulthood, also when controlling partially for genetic background, and that menopause may not contribute to this decline.
Association between vasomotor symptom frequency and weight gain in the Study of Women's Health Across the Nation
s the Nation. Women in premenopause or perimenopause aged 42 to 52 years at baseline self-reported VMS frequency (hot flashes/night sweats) and sleep problems at up to 10 annual visits....
Conclusion: This study demonstrates that increases in VMS, onset of a high frequency of VMS, and persistent VMS symptoms over time may precede weight gain in women.
Reproductive Experiences and Cardiovascular Disease Care in Pregnancy-Capable and Postmenopausal Individuals: Insights from the American Heart Association Research Goes Red Registry
Source : https://www.sciencedirect.com/science/article/pii/S0146280623002700
To evaluate preconception health and adverse pregnancy outcome (APO) awareness in a large population-based registry.We examined data from the Fertilit...
Conclusion: There is an urgent, ongoing need for more education on APOs and CVD risk, to improve the health-care experiences and postpartum health outcomes of pregnant individuals.
The effect of mobile app-based self-care training on the quality of marital relations and the severity of menopausal symptoms in postmenopausal women: a clinical trial study in Iran - BMC Women's Health
Source : https://bmcwomenshealth.biomedcentral.com/articles/10.1186/s12905-023-02463-4
Background Educational interventions for self-care are a necessary solution to help postmenopausal women properly deal with menopausal problems. The present study aimed to investigate the effect of self-care training using...
Conclusion: Implementation of a self-care training program through the application helped improve the quality of marital relations and reduce the severity of postmenopausal women's symptoms, so it can be used as an effective method to prevent the unpleasant consequences of menopause.
Early menopause is associated with increased risk of heart failure and atrial fibrillation: A systematic review and meta-analysis
Source : https://www.sciencedirect.com/science/article/pii/S037851222300378X
Menopause is linked to a higher risk of cardiovascular disease. However, it is unclear whether premature menopause (defined as menopause before the ag...
Conclusion: Women who undergo premature menopause or early menopause have a higher risk of heart failure and atrial fibrillation compared with women who undergo menopause in the normal age range. These reproductive factors need to be considered for measures that might reduce the risk of heart failure and atrial fibrillation.
Vasomotor and other menopause symptoms and the prevalence of ideal cardiovascular health metrics among premenopausal stage women
g health screening examinations. Menopause symptoms were measured using the Korean version of the Menopause-Specific Quality of Life questionnaire. For vasomotor, psychosocial, physical, and sexual symptoms, participants were divided into...
Conclusion: Premenopausal stage women with either vasomotor or nonvasomotor menopausal symptoms have significantly higher prevalence of poor CVH metrics, compared with those without any menopausal symptoms.
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Menopause Connect3yrKey Points • Source: Menopause • Conclusions: “Premenopausal stage women with either vasomotor or nonvasomotor menopausal symptoms have significantly higher prevalence of poor CVH [cardiovascular health] metrics, compared with those without any menopausal symptoms.” • In Show More
Support of adult urinary incontinence products: recommendations to assure safety and regulatory compliance through application of a risk assessment framework
Source : https://www.frontiersin.org/articles/10.3389/frph.2023.1175627/full
Urinary incontinence (UI) or involuntary loss of urine is a common chronic medical condition among women. It is estimated that 5%−70% of the population experiences incontinence with most studies suggesting...
Discussion: This risk assessment indicates that the likelihood of a toxic effect from the incontinence products is negligible and that the device should be considered safe for use as intended. The evaluation of these AI products takes into consideration the exposure-based risk assessment results from the evaluation of each individual supplier...
Anticipated age of perimenopausal experiences, stress, satisfaction, and health and well-being: observations from the Women Living Better Survey - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37279510/
Being "off-time" alone had little effect on studied measures with the exception of poorer perceived health. Experiencing more noticeable perimenopause-related menstrual cycle changes or having more bothersome vasomotor symptoms influenced...
Conclusion: These interactive effects of being “off-time” and experiencing volatile mood suggest a need for greater attention to the link between volatile mood and perimenopause. Furthermore, anticipatory guidance for those on the path to menopause should include the possibility of volatile mood symptoms.
Vasomotor and other menopause symptoms and the prevalence of ideal cardiovascular health metrics among premenopausal stage women
g health screening examinations. Menopause symptoms were measured using the Korean version of the Menopause-Specific Quality of Life questionnaire. For vasomotor, psychosocial, physical, and sexual symptoms, participants were divided into...
Conclusion: Premenopausal stage women with either vasomotor or nonvasomotor menopausal symptoms have significantly higher prevalence of poor CVH metrics, compared with those without any menopausal symptoms.
Associations of LH and FSH with reproductive hormones depending on each stage of the menopausal transition - BMC Women's Health
Source : https://bmcwomenshealth.biomedcentral.com/articles/10.1186/s12905-023-02438-5
Introduction Associations of luteinizing hormone (LH) with androgens during the menopausal transition and associations between follicle-stimulating hormone (FSH) levels and various diseases related to reproductive hormones in postmenopause have received...
Conclusion: The associations of LH and FSH with reproductive hormones are different depending on the stage of the menopausal transition.
Mental health and quality of life in post-menopausal women as a function of retrospective menopause symptom severity
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178181/
Savannah C. Hooper, BA, 1, 2, * Victoria B. Marshall, BA, 1, 2 Carolyn B. Becker, PhD, 3 Andrea Z. LaCroix, PhD, 4 Pamela K. Keel, PhD, 5 and Lisa...
Conclusion: The menopausal transition is a significant change in a woman’s life and the challenges of menopausal symptoms can have lasting impacts on women’s health. It is imperative that future research seeks to further understand the lasting impacts of this transition on the lives of older women to ensure proper interventions are...
The effect of Crocus sativus L. (saffron) herbal tea on happiness in postmenopausal women: a randomized controlled trial - BMC Complementary Medicine and Therapies
Source : https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-023-04014-8
Background Evidence suggests that menopause can be associated with a variety of negative psychological changes such as depression and anxiety, and improving the mental health status of women during menopause...
Conclusion: Saffron herbal tea had a positive effect on reducing depression and increasing the happiness score; thus, it is recommended that it should be used as a complementary treatment in consultation with the treating physician.
Factors associated with weight gain in pre- and post-menopausal women receiving adjuvant endocrine therapy for breast cancer - Journal of Cancer Survivorship
Source : https://link.springer.com/article/10.1007/s11764-023-01408-y
Purpose Weight gain after breast cancer poses health risks. We aimed to identify factors associated with weight gain during adjuvant endocrine therapy (AET). Methods Women initiating AET enrolled in a...
Conclusion: Weight gain during AET is common, especially for pre-menopausal women. Clinicodemographic features and early treatment-emergent symptoms may identify at risk individuals.
Sex and gender influence on immunity and autoimmunity
Source : https://www.frontiersin.org/articles/10.3389/fimmu.2023.1142723/full
Autoimmune diseases are skewed toward one biological sex or another. This is the obvious observation of many decades, and it remains unexplained. Females predominate with most autoimmune diseases. The reasons...
Conclusion: The interplay between genetics and sex steroid metabolism within the body is how the immune response handles infections and regulates immune function. The reasons for the female predilection for autoimmune disease remains unknown but is likely due to the genetics of the X chromosome, hormonal regulation of immune cells (CD4 T...
Investigating the efficacy and feasibility of using a whole-of-diet approach to lower circulating levels of C-reactive protein in postmenopausal women: a mixed methods pilot study
protein in weight stable postmenopausal women with abdominal obesity. Methods This mixed-methods pilot study used a single arm pre-post design. Thirteen women followed a 4-week anti-inflammatory, dietary intervention, optimizing consumption...
Conclusion: Weight-neutral dietary interventions targeting inflammation can improve metabolic markers and may be a viable strategy for CVD risk reduction in postmenopausal women. To determine effects on inflammatory status, a fully powered and longer-term randomized controlled trial is required.