Despite RKSK, only 12.5% of facilities offer adolescent services. Barriers include privacy issues and staff shortages; opportunities lie in digital health and community engagement.

Severe intolerance to swallowable balloons in a 41-year-old man with obesity may indicate hiatal issues. Laparoscopic removal, hiatal repair, and gastric bypass were effective interventions.

LPCAT3 remodels phospholipids, impacting autophagy, endoplasmic reticulum homeostasis, and inflammation, relevant to diabetes and NAFLD in primary care.

The study examines long-term effects of pregnancy lifestyle interventions on offspring using DXA scans and glucose monitoring in a follow-up of a randomized controlled trial.

A Mediterranean diet intervention significantly reduced uncontrolled eating (p=0.0226) and increased cognitive restraint (p=0.0004) without altering metabolic markers.

Sleeve gastrectomy alters faecal SCFA profiles over 12 months, with decreased major SCFAs and increased branched SCFAs, suggesting gut microbiota shifts.

Cross-sectional study found that postural stability in children is influenced by age, physical activity, physical education performance, and body weight, with overweight/obesity associated with poorer balance measures and sports participation potentially mitigating some deficits.

Case suggests a potential association between tirzepatide and recurrent hyponatremia, particularly with concomitant chlorthalidone use, highlighting the importance of serum sodium monitoring during GLP-1 receptor agonist therapy.

This review examines leptin biology and mechanisms of leptin resistance in obesity, highlighting impaired signaling pathways, inflammation, and hyperleptinemia while discussing emerging strategies including leptin sensitization, combination therapies, and MC4R agonists.

This systematic review highlights how obesity complicates breast cancer care through diagnostic delays, surgical complications, altered drug metabolism, treatment toxicity, and multimorbidity, emphasizing the need for personalized obesity-specific management strategies.

Cholesterol-lowering drugs may influence atopic dermatitis via skin barrier effects, but evidence is inconclusive; statins/NPC1L1 inhibitors show concern, PCSK9 inhibitors may protect; prioritize cardiovascular benefits while monitoring dermatitis.

Review highlights importance of early, personalized ICU nutrition using enteral feeding, adequate protein, and AI/metabolomics integration to improve outcomes, reduce complications, and enable precise, multidisciplinary nutritional care.

Obesity accelerates cardiovascular aging through shared mechanisms like inflammation and mitochondrial dysfunction; weight reduction and metabolic therapies may counteract these processes, reducing cardiovascular disease risk and improving longevity.