Obesity-Related Hemodynamic Alterations in Patients With Cushing's Disease
Source : https://www.mdpi.com/2077-0383/13/6/1658
Background: Cushing's disease (CD) is associated with a specific form of metabolic syndrome that includes visceral obesity, which may affect cardiovascular hemodynamics by stimulating hypercortisolism-related metabolic activity. The purpose of...
Use of novel diagnostic modalities demonstrated that excessive fat accumulation in young and middle-aged patients with Cushing disease, already at the early stages of the disease, is associated with some hemodynamic changes in the CV system.
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Efficacy and Safety of Tirzepatide in Overweight and Obese Adult Patients With Type 1 Diabetes
Source : https://pubmed.ncbi.nlm.nih.gov/38512447/
In this pilot (off-label) study, we conclude that tirzepatide facilitated an average 18.5% weight loss (>46 pounds) and improved glucose control in OW/OB patients with T1D at one year. For...
There were significantly larger declines in BMI and weight in the treated group than controls across all time points among those in whom data were available.
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Mean changes in bodyweight from baseline to week 46 were –6.2%, –12.5%, –13.2%, –14.9%, and –2.8%.
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In this cross-sectional study of 5229 individuals, prevalence of obesity was highest among people who identified as Asian, Pacific Islander, and White (52.0%).
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These findings suggest that sarcopenic obesity may be associated with worse survival, and conducting screening for muscle function may help prevent premature death among older people.
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