Efficacy and Safety of Once Weekly Semaglutide 2·4 mg for Weight Management in a Predominantly East Asian Population With Overweight or Obesity (STEP 7): a Double-Blind, Multicentre, Randomised Controlled Trial
Source : https://pubmed.ncbi.nlm.nih.gov/38330988/
For the Mandarin, Portuguese and South Korean translations of the abstract see Supplementary Materials section.
At week 44, the proportion of participants who lost 5% or more of their bodyweight was higher in the semaglutide 2.4 mg group than in the placebo group.
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Exploring the Association Between Suicidal Thoughts, Self-Injury, and GLP-1 Receptor Agonists in Weight Loss Treatments: Insights From Pharmacovigilance Measures and Unmasking Analysis
Source : https://pubmed.ncbi.nlm.nih.gov/38508100/
With the current pharmacovigilance approach, no causality link between suicidal ideation and use of any GLP-1 RA can be inferred. There is a need for further research and vigilance in...
The authors postulated that rapid weight loss achieved with GLP-1 receptor agonists could potentially trigger significant emotional, biologic, and psychological responses, possibly impacting suicidal and self-injurious ideations.
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A Low-Burden, Self-Weighing Intervention to Prevent Weight Gain in Adults With Obesity Who Do Not Enroll in Comprehensive Treatment
Source : https://pubmed.ncbi.nlm.nih.gov/38510333
A low-burden self-weighing intervention can reach adults with overweight/obesity who would be unlikely to engage in comprehensive weight loss programs; the efficacy of this intervention for preventing weight gain should...
This feasibility trial showed that a meaningful portion of adults with obesity who do not enroll in a comprehensive weight loss program would enroll in a low burden, remotely delivered self‐weighing program.
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Experiences and Outcomes of Indigenous Patients Undergoing Bariatric Surgery: a Mixed-Method Scoping Review
Source : https://pubmed.ncbi.nlm.nih.gov/38400946/
Obesity and type 2 diabetes (T2D) are growing global health concerns. Evidence suggests that Indigenous peoples are at higher lifetime risk of obesity and its associated conditions. Obesity increases the...
Indigenous patients had fewer bariatric procedures, poorer clinic attendance, similar weight loss outcomes, and slightly higher postoperative complication rates.
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In this cohort study of 1229 individuals who participated in the Look AHEAD trial, incorporating high physical activity volume and weight loss was associated with a 61% of lower risk of adverse CV events.
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