1yr
Share
1yr
Obesity and its comorbidities, current treatment options and future perspectives: Challenging bariatric surgery? - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37879540/
Obesity and its comorbidities, including type 2 diabetes mellitus, cardiovascular disease, heart failure and non-alcoholic liver disease are a major health and economic burden with steadily increasing numbers worldwide. The...
The article reviews obesity and its comorbidities, highlighting organ-specific mechanisms, effective treatments like bariatric surgery, emerging pharmacological options, and the potential of targeting the gut-brain axis for future therapies.
Share
1yr
Obesity Management in Adults: A Review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38015216/
Obesity affects approximately 42% of adults in the US. Behavioral interventions can attain approximately 5% to 10% weight loss, GLP-1 agonists and glucose-dependent insulinotropic polypeptide/GLP-1 receptor agonists can attain approximately...
Obesity affects 42% of US adults, increasing health risks. Effective treatments include behavioral interventions, GLP-1 agonists, and bariatric surgery, achieving 5-30% weight loss based on individual needs.
Share
1yr
Caloric Restriction Intervention Alters Specific Circulating Biomarkers of the Senescence-Associated Secretome in Middle-Aged and Older Adults With Obesity and Prediabetes in an 18-Week Randomized Controlled Trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37738560/
Cellular senescence is a biological aging process that is exacerbated by obesity and leads to inflammation and age- and obesogenic-driven chronic diseases including type 2 diabetes. Caloric restriction (CR) may...
Caloric restriction in middle-aged adults with obesity and prediabetes significantly alters circulating SASP biomarkers, though T-cell senescence markers remain unchanged, indicating reduced senescent cell burden linked to weight loss.
Share
1yr
Childhood obesity from the genes to the epigenome - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39045266/
The prevalence of obesity and its associated comorbidities has surged dramatically in recent decades. Especially concerning is the increased rate of childhood obesity, resulting in diseases traditionally associated only with...
Obesity's transgenerational inheritance, driven by epigenetic mechanisms from parental obesity, contributes to offspring's increased body weight and long-term cardiometabolic risks, offering insights for improved clinical management and prevention strategies.
Share