Sarcopenic obesity and osteoporosis: Research progress and hot spots
Source : https://pubmed.ncbi.nlm.nih.gov/39147076/
Sarcopenic obesity (SO) and osteoporosis (OP) are associated with aging and obesity. The pathogenesis of SO is complex, including glucolipid and skeletal muscle metabolic disorders caused by inflammation, insulin resistance,...
Sarcopenic obesity and osteoporosis are interrelated through muscle-lipid metabolism and inflammation. Addressing both conditions requires exploring new therapeutic targets and combining exercise with diet for improved musculoskeletal health.
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Novel hypothalamic pathways for metabolic effects of spexin
Source : https://pubmed.ncbi.nlm.nih.gov/39245191/
One of the main underlying etiologies of type 2 diabetes (T2DM) is insulin resistance, which is most frequently caused by obesity. Notably, the deregulation of adipokine secretion from visceral adiposity...
Spexin's role in regulating energy metabolism and homeostasis, through hypothalamic melanocortin pathways, highlights its potential as a therapeutic target for addressing obesity, insulin resistance, and type 2 diabetes.
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Immunological roles for resistin and related adipokines in obesity-associated tumors - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39232363/
Rationale Obesity is an independent risk factor for the occurrence and development of tumors. Obesity is influenced by signaling of adipokines, which are secreted factors from adipocytes and resident immune...
Resistin and other adipokines play crucial roles in obesity-related tumor development, highlighting their potential as targets for novel anti-tumor strategies to limit tumor growth and manage obesity simultaneously.
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The interaction of breastfeeding and genetic factors on childhood obesity - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39224127/
Childhood obesity represents a pressing global public health concern due to its widespread prevalence and its close connection to early-life exposure to risk factors. The onset of obesity is contingent...
In conclusion, breastfeeding significantly influences childhood obesity risk through genetic factors and epigenetic mechanisms, emphasizing its importance in public health strategies to mitigate obesity prevalence.
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Association of Cellulitis With Obesity: Systematic Review and Meta-Analysis - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39163102/
Our findings suggest that cellulitis is significantly associated with obesity. Maintaining a healthy BMI may be indicated for patients presenting with cellulitis.
This systematic review and meta-analysis found a significant association between cellulitis and obesity, highlighting the importance of maintaining a healthy BMI in affected patients.
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