The prevalence of obesity is expected to reach 49% by 2023, and this chronic, relapsing disease is linked to comorbidities, including T2DM, dyslipidemia, hypertension, CAD, stroke, and certain cancers. The total financial costs of chronic conditions linked to obesity are estimated at $1.71 trillion. The effective weight management of patients with obesity is necessary to optimize quality of life, minimize medical and financial costs, and decrease morbidity and mortality.
Various weight-loss interventions have been developed, including diet/exercise lifestyle interventions; antiobesity medications (AOMs); surgical interventions, and endoscopic interventions. AOMs are effective and improve quality of life and decrease the risk of weight-related comorbidities. Nevertheless, AOMs demonstrate a wide variation in the percentage of weight loss, between 5% and 12%, per the results of clinical trials.
Five FDA-approved AOMs are semaglutide, liraglutide, orlistat, phentermine plus topiramate, and naltrexone plus bupropion. These drugs are indicated for long-term use in patients with a BMI ≥ 30 without weight-related comorbidities and a BMI ≥ 27 in those with weight-related comorbidities.
Are you discussing anti-obesity medications with your patients more proactively? Please share your current comfort in prescribing anti-obesity medications.
I’m discussing weight loss and new treatments with patients regularly…in fact most of them have knowledge of the Glp1 class and Mounjaro and they seem to be accepting of them…I recommend them as well as Contrave regularly.
Especially now there are newer medications to treat obesity like ozempic, wegovy , mounjaro which are very effective to treat obesity with weight loss of up to 25%