Interpretation: COVID-19 deaths and hospital admissions were higher in people with immune-mediated inflammatory diseases. We saw no increased risk of adverse COVID-19 outcomes in those on most targeted immune-modifying drugs for immune-mediated inflammatory diseases compared with those on standard systemic therapy.
Interpretation: The ability of high-throughput serological assays to predict neutralising antibody titres is likely to be crucial for evaluation of immunity at the population scale. These data can facilitate the selection of the most suitable assays as surrogates of functional neutralising activity and suggest that such measurements might be...
Intradermal Testing With COVID-19 mRNA Vaccines Predicts Tolerance
Source : https://doi.org/10.3389/falgy.2022.818049
BackgroundThe newly developed mRNA-based COVID-19 vaccines can provoke anaphylaxis, possibly induced by polyethylene glycol (PEG) contained in the vaccine. The management of persons with a history of PEG allergy or...
Conclusion: Sensitization to SARS-CoV-2 mRNA vaccines can be detected with intradermal testing. Significantly more individuals were sensitized to mRNA vaccines in the post-vaccination cohort. A two-step 10–90%-vaccination protocol can be safely administered upon negative skin testing.
Food allergy is associated with lower risk of SARS-CoV-2 infection
NIH study finds high BMI and obesity raise infection risk, but asthma does not. A National Institutes of Health-funded study has found that people with food allergies are less likely...
NIH study finds high BMI and obesity raise infection risk, but asthma does not.
Allergological study in patients vaccinated against COVID-19 with suspected allergic reactions - Allergy, Asthma & Clinical Immunology
Source : https://aacijournal.biomedcentral.com/articles/10.1186/s13223-022-00685-z
Background One of the main barriers to vaccination against SARS-CoV-2 is the fear of developing hypersensitivity reactions to any of its components. Although these reactions are very rare, it is...
Conclusions: Thanks to the allergological and immunohistochemical study, the vaccination protocol could be completed in about half of the patients who presented suspected hypersensitivity reactions to SARS-CoV-2 vaccines. IDTs with vaccines could be a valuable method for assessing the immunogenicity of the vaccines.