Asthma Outcome Measures Before and After the COVID-19 Outbreak Among the Pediatric Population in a Community Hospital
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is a global health threat that has affected patient care enormously. Moderate to severe asthma was listed as a risk...
Conclusion: Among a majority African American pediatric population, there were significant improvements in asthma outcomes after COVID-19 societal changes when compared to before COVID-19 based on outcome variables.
Brain motor and fear circuits regulate leukocytes during acute stress - Nature
Source : https://www.nature.com/articles/s41586-022-04890-z
The nervous and immune systems are intricately linked1. Although psychological stress is known to modulate immune function, mechanistic pathways linking stress networks in the brain to peripheral leukocytes remain poorly...
Collectively, these data show that distinct brain regions differentially and rapidly tailor the leukocyte landscape during psychological stress, thus calibrating the immune system’s capacity to respond to physical threats.
Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections: Update of a living systematic review and meta-analysis
Source : https://doi.org/10.1371/journal.pmed.1003987
Diana Buitrago-Garcia, Aziz Mert Ipekci, Leonie Heron, Hira Imeri, Lucia Araujo-Chaveron, Ingrid Arevalo-Rodriguez, Agustín Ciapponi, Muge Cevik, Anthony Hauser, Muhammad Irfanul Alam Subject Areas For more information about PLOS Subject...
Conclusions: Based on studies published up to July 2021, most SARS-CoV-2 infections were not persistently asymptomatic, and asymptomatic infections were less infectious than symptomatic infections. Summary estimates from meta-analysis may be misleading when variability between studies is extreme and prediction intervals should be presented....
Evaluation of mRNA-1273 Covid-19 Vaccine in Children 6 to 11 Years of Age | NEJM
Source : https://www.nejm.org/doi/full/10.1056/NEJMoa2203315
Original Article List of authors. C. Buddy Creech, M.D., M.P.H., Evan Anderson, M.D., Vladimir Berthaud, M.D., M.P.H., Inci Yildirim, M.D., Ph.D., Andrew M. Atz, M.D., Ivan Melendez Baez, M.D., Daniel...
CONCLUSIONS: Two 50-μg doses of the mRNA-1273 vaccine were found to be safe and effective in inducing immune responses and preventing Covid-19 in children 6 to 11 years of age; these responses were noninferior to those in young adults.
Pioneering study identifies global dynamics of Antibiotic Resistance
Source : https://www.exeter.ac.uk/news/homepage/title_913713_en.html
Antibiotic resistance is recognised as being one of the most significant threats to global health Scientists have used ideas from artificial intelligence to identify patterns of antibiotic resistance around the...
We sought data anomalies whereby MICs could shift for methodological and not clinical or microbiological reasons and found artefacts in over 100 pathogen-antibiotic pairs. Using an information-optimal clustering methodology to classify pathogens into low and high antibiotic susceptibilities, we used ATLAS to predict changes in resistance....