Type 2 Diabetes Connect
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Combination of disease duration-to-age at diagnosis and hemoglobin A1c-to-serum C-peptide reactivity ratios predicts patient response to glucose-lowering medication in type 2 diabetes: A retrospective cohort study across Japan (JDDM59) - PubMed

Combination of disease duration-to-age at diagnosis and hemoglobin A1c-to-serum C-peptide reactivity ratios predicts patient response to glucose-lowering medication in type 2 diabetes: A retrospective cohort study across Japan (JDDM59) - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33837666/

1 Diabetes Center, Chiba Central Medical Center, Chiba, Japan. 2 Department of Preventive Medicine and Public Health, Keio University School of Medicine Graduate School of Medicine, Tokyo, Japan. 3 Kawai...



Conclusions: The combination of disease duration-to-age at diagnosis and HbA1c-to-CPR ratios is a collective risk factor that predicts response to the medications.

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Relationships of Changes in Physical Activity and Sedentary Behavior With Changes in Physical Fitness and Cardiometabolic Risk Profile in Individuals With Type 2 Diabetes: The Italian Diabetes and Exercise Study 2 (IDES_2) - PubMed

Relationships of Changes in Physical Activity and Sedentary Behavior With Changes in Physical Fitness and Cardiometabolic Risk Profile in Individuals With Type 2 Diabetes: The Italian Diabetes and Exercise Study 2 (IDES_2) - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34728529/

Objective: In the Italian Diabetes and Exercise Study_2 (IDES_2), behavioral counseling promoted a sustained increase in physical activity (PA) volume (+3.3 MET h ⋅ week-1), moderate- to vigorous-intensity PA (MVPA)...



Conclusions: Even modest increments in MVPA may have a clinically meaningful impact, and reallocating SED-time to LPA may also contribute to improved outcomes, possibly by increasing total energy expenditure.


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What would be your treatment step to get patient at goal?

56-year old female with type 2 diabetes, BMI of 30 kg/m2 and no major comorbidities, has been on metformin and a sulfonylurea at their highest tolerated doses. Four months ago, her previous physician added a high dose of a DPP-IV inhibitor to help get her to goal of 7%. The treatment regimen brought the A1C to 7.6%. The patient is seeking a second opinion.



Would you consider switching any medications or adding on? Please list what would be your preferred options.


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4yr
What would be your treatment step to get patient at goal?

56-year old female with type 2 diabetes, BMI of 30 kg/m2 and no major comorbidities, has been on metformin and a sulfonylurea at their highest tolerated doses. Four months ago, her previous physician added a high dose of a DPP-IV inhibitor to help get her to goal of 7%. The treatment regimen brought the A1C to 7.6%. The patient is seeking a second opinion.



Would you consider switching any medications or adding on? Please list what would be your preferred options.


Show More Comments

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made a Post

4yr
What would be your treatment step to get patient at goal?

56-year old female with type 2 diabetes, BMI of 30 kg/m2 and no major comorbidities, has been on metformin and a sulfonylurea at their highest tolerated doses. Four months ago, her previous physician added a high dose of a DPP-IV inhibitor to help get her to goal of 7%. The treatment regimen brought the A1C to 7.6%. The patient is seeking a second opinion.



Would you consider switching any medications or adding on? Please list what would be your preferred options.


Show More Comments