Myopia and Early Onset Type 2 Diabetes: A Nationwide Cohort Study
Source : https://academic.oup.com/jcem/advance-article-abstract/doi/10.1210/clinem/dgab669/6368107
AbstractObjective. A correlation between myopia and insulin-resistance has been suggested. We investigated the association between myopia in adolescence and typ
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Dr Hamid4yrFor women, myopia in adolescence was associated with a significantly increased risk for incident T2D in young adulthood, in a severity-dependent manner
Functional characterization of T2D-associated SNP effects on baseline and ER stress-responsive β cell transcriptional activation - Nature Communications
Source : https://www.nature.com/articles/s41467-021-25514-6
Identifying causal variants at GWAS loci is important to understand disease mechanisms. Here the authors use massively parallel reporter assays to identify type 2 diabetes-associated variants that alter cis-regulatory activity,...
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Type 2 Diabetes Connect4yrKey Points • Conclusion/Relevance: “In this study, we tested 13,252 sequences containing alleles of 6,621 SNPs for their ability to activate and modulate transcription in MIN6 β cells under standard culture conditions Show More
Comparison of patient- and clinician-reported outcome measures in lower back rehabilitation: introducing a new integrated performance measure (t2D) - Quality of Life Research
Source : https://link.springer.com/article/10.1007/s11136-021-02905-2
Purpose Patient- and clinician-reported outcome measures (PROMs, CROMs) are used in rehabilitation to evaluate and track the patient's health status and recovery. However, controversy still exists regarding their relevance and...
Incidence of COVID-19 and Risk of Diabetic Ketoacidosis in New-Onset Type 1 Diabetes - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34011636/
1 Division of Pediatric Endocrinology and Diabetology, Centre of Child and Adolescent Medicine, Justus Liebig University, Giessen, Germany [email protected]. 2 Institute for Biometrics and Epidemiology, German Diabetes Centre, Leibniz Centre...
Variability in body weight and the risk of cardiovascular complications in type 2 diabetes: results from the Swedish National Diabetes Register - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34446018/
High body weight variability predicts the development of cardiovascular complications in type 2 diabetes. These data suggest that any strategy to reduce the body weight in these subjects should be...
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Anonymous User4yrHigh body weight variability predicts the development of cardiovascular complications in type 2 diabetes !!!
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Type 2 Diabetes Connect4yrKey Points • Conclusion: “High body weight variability predicts the development of cardiovascular complications in type 2 diabetes. These data suggest that any strategy to reduce the body weight in these Show More