Conclusion: We found that oxidative stress, as evaluated by d-ROMs, was significantly higher in postmenopausal women than in premenopausal counterparts. However, there were no significant shifts in oxidative stress markers during the menstrual cycle. Additional studies are needed to fully understand the mechanisms by which endogenous estrogen...

Conclusion: Nutritional interventions are promising tools for the management of mood/anxiety symptoms in women during the menopausal transition and in postmenopausal years. Because of significant heterogeneity and risk of bias among studies, the actual effect of different approaches is still unclear.

Conclusion: Postmenopausal women were more influenced by mixed heavy metals' effects on kidney function than premenopausal women. Early interventions (eg, water filtering, heavy metal yearly screening) in women, especially postmenopausal women, are needed to reduce the incidence of chronic kidney disease.

Conclusion: We have demonstrated here that some of the basic clinical variables related to men- strual status, such as time from last menstruation or postoperative FSH concentration, may contribute to overall survival in endometrial cancer patients.

Conclusion: Our findings suggest that a longer duration since menopause is associated with alterations of the lipid profile (lower HLD-C and higher LDL-C levels) in postmenopausal women. However, more studies, especially large prospective studies, are needed to explore this relationship and further reveal the underlying mechanisms.

Discussion: We found a decreased systemic HT prevalence and an increased mortality risk for systemic HT users in both study populations in the wake of the 2002 WHI publication with the most pronounced tendency presented in the singleton population. The findings suggest an alteration in the HT user profile after 2002 with a different pattern of...

Conclusion: Pycnogenol intake significantly increased hair density by 30% and 23% after 2 and 6 months of treatment, respectively, as detected by Trichoscan evaluation of digital photographs. Interestingly, photoplethysmography revealed that this beneficial effect was associated with a decrease in resting flux of the scalp skin, which might...

Conclusion: We observed no differences in vascular function between healthy, active pre- and postmenopausal females. After accounting for age, there was no difference in cerebrovascular function between groups, and there were no associations between reproductive hormone levels, vascular function and NO bioavailability.

Conclusion: Considering the studies encountered, strength exercises can be beneficial for improving menopausal symptoms that affect muscle performance in general, physical activity, bone density and hormonal and metabolic responses such as heart rate, blood pressure and hot flashes. In terms of the appropriate type of strength training, the...

Conclusion: The meta-analysis reveals that menopausal status was associated with approximately 2.4 times higher odds of NAFLD.

Conclusions: If all results are normal and the patient has had at least 3 normal cytology results or 2 normal HPV tests during the past 10 years, then the patient may stop cervical cancer screening at age 65 years. However, patients should continue to be screened even if they are older than 65 years if they have not been previously screened or...

Conclusions: Our study evidenced that GSM is prevalent in old age Chinese women. GSM is related with UI, POP and VVA. Further older age, menopause and FI were risk factors associated with VVA. Our findings could help health care personnel to get a comprehensive overview of factors associated with VVA and urinal distress, which may facilitate...

Conclusions: The findings presented by Christmas et al provide insight into menopause treatment usage rates and how HT and CAM influence QoL by race/ethnicity. The disparate burden of untreated menopause symptoms in Black women and other women of color serves as a call to action to stimulate more research in this area.

Conclusions: The present 31P-MRS study of middle-aged individuals at risk for AD indicates sex differences in brain metabolic function of AD-vulnerable regions during midlife endocrine aging. Such changes may increase susceptibility to AD in women and provide a window of opportunity for precision medicine based preventative strategies.

Conclusion: Comparisons between treatment type within each racial/ethnic group yielded significant differences in self-reported QoL. Clinicians should be aware of racial/ethnic differences in treatment preferences when counseling patients on treatment options for menopausal symptoms to provide optimal care.

Discussion: To provide optimal care throughout the menopause transition, healthcare providers need to provide a comprehensive evaluation including assessment of medical history and current status, psychosocial and cultural background, and individual personal and subjective perspectives. Personal and tailored healthcare according to a woman’s...

Conclusion: Although menopause is known to adversely affect structures and functions related to swallowing such as bone, muscle, and mucosa of the upper aerodigestive tract, saliva, and taste, the relationship between menopause and swallowing functions remains poorly understood. By identifying the major gaps in the literature, these results...

Discussion: There was very low-quality evidence supporting the benefits of RT compared with control for C-reactive protein levels and lipid profile. No benefits were found for the outcome of waist circumference in postmenopausal women with different comorbidities or risk factors.

Conclusion: No matter influenced by which factors, life stages such as puberty and menopause are the indication of significant changes in human development. Because the ages of puberty among individuals or ethnic groups are different, instruction of doses is better based on puberty rather than ages.

Conclusion: Recent large scale genomic studies have started to elucidate how genetic variation affects variation in the ANM and importantly has informed functional experiments targeting specific molecular players for pharmacological or life-style treatments. Following the example of other complex traits, larger cohorts are anticipated to expand...